Huntingtin Protein

Known as: Huntingtin Protein [Chemical/Ingredient], Huntington Disease Protein, IT15 Protein 
A protein that is highly expressed in the nervous system as well as other tissues; its size and structure vary due to polymorphisms. Expanded CAG… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0204019972017

Papers overview

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Review
2016
Review
2016
Cerebrospinal fluid (CSF) is enriched in brain-derived components and represents an accessible and appealing means of… (More)
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Highly Cited
2014
Highly Cited
2014
Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an extended polyglutamine repeat in the N terminus of… (More)
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Highly Cited
2010
Highly Cited
2010
Huntington's Disease (HD) is a dominantly inherited pathology caused by the accumulation of mutant huntingtin protein (HTT… (More)
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Highly Cited
2009
Highly Cited
2009
Huntington's disease is caused by an expanded CAG repeat in the gene encoding huntingtin (HTT), resulting in loss of striatal and… (More)
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Highly Cited
2006
Highly Cited
2006
Huntington's disease (HD) is an inherited neurodegenerative disease caused by a glutamine repeat expansion in huntingtin protein… (More)
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Highly Cited
2006
Highly Cited
2006
Huntington's disease (HD) is a devastating neurodegenerative disorder caused by an expanded polyglutamine (polyQ) tract within… (More)
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Highly Cited
2004
Highly Cited
2004
Huntington's disease (HD) is initiated by an abnormally expanded polyglutamine stretch in the huntingtin protein, conferring a… (More)
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Highly Cited
2002
Highly Cited
2002
Huntington's disease (HD) is caused by an expansion of exonic CAG triplet repeats in the gene encoding huntingtin protein (Htt… (More)
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Highly Cited
2002
Highly Cited
2002
Both transcriptional dysregulation and proteolysis of mutant huntingtin (htt) are postulated to be important components of… (More)
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Highly Cited
2001
Highly Cited
2001
The huntingtin exon 1 proteins with a polyglutamine repeat in the pathological range (51 or 83 glutamines), but not with a… (More)
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