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Humanized Monoclonal Antibody 3F8

Known as: Hu3F8, Humanized Anti-GD2 Antibody 3F8 
A humanized monoclonal antibody directed against the human tumor-associated antigen GD2, with potential antineoplastic activity. Upon vaccination… Expand
National Institutes of Health

Papers overview

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2018
2018
Importance Chimeric and murine anti-GD2 antibodies are active against neuroblastoma, but the development of neutralizing… Expand
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2017
2017
ABSTRACT Fifty-seven stage 4 patients with refractory/relapsed neuroblastoma were enrolled in a phase I trial (Clinicaltrials.gov… Expand
2015
2015
Background: Modest affinity to carbohydrate targets limits the therapeutic efficacy of antibodies to tumor antigens, such as… Expand
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2014
2014
Bispecific antibodies (BsAb) haveproven to beuseful targeting vectors for pretargeted radioimmunotherapy (PRIT). We sought to… Expand
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Highly Cited
2012
Highly Cited
2012
Murine IgG3 anti-GD2 antibody m3F8 has shown anti-neuroblastoma activity in Phase I/II studies, where antibody-dependent cell… Expand