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Human Glandular Kallikrein 2

Known as: hK2 Kallikrein, Glandular Kallikrein 2 Precursor, Prostate Specific Kallikrein 
Kallikrein-2 (261 aa, ~29 kDa) is encoded by the human KLK2 gene. This protein plays a role in proteolysis and vasodilation.
National Institutes of Health

Related topics

Related topics

14 relations
Androgen Receptor Regulation PathwayEnzyme GeneHomo sapiensHuman Glandular Kallikrein 1

Broader (1)

Tissue Kallikrein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Human tissue kallikrein gene family: applications in cancer.
Review
2002
Review
2002
Human tissue kallikreins: a family of new cancer biomarkers.
Kallikreins are a subgroup of the serine protease enzyme family. Until recently, it was thought that the human kallikrein gene… 
Highly Cited
2001
Highly Cited
2001
Quercetin inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells.
The androgen receptor (AR) is involved in the development and progression of prostate cancer. In order to find new compounds that… 
Highly Cited
1998
Highly Cited
1998
Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes.
The human prostate cancer (CaP) xenograft, CWR22, mimics human CaP. CWR22 grows in testosterone-stimulated nude mice, regresses… 
Highly Cited
1997
Highly Cited
1997
Activation of the zymogen form of prostate-specific antigen by human glandular kallikrein 2.
Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are glandular kallikreins secreted by the prostate gland… 
Highly Cited
1993
Highly Cited
1993
A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression
The electrophysiological properties of HK2 (Kv1.5), a K+ channel cloned from human ventricle, were investigated after stable… 
Highly Cited
1989
Highly Cited
1989
Characterization of the prostate-specific antigen gene: a novel human kallikrein-like gene.
Highly Cited
1989
Highly Cited
1989
Characterization of the gene for prostate-specific antigen, a human glandular kallikrein.
Highly Cited
1988
Highly Cited
1988
Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.
Highly Cited
1987
Highly Cited
1987
Primary structure of a human glandular kallikrein gene.
To isolate a human glandular kallikrein gene, a human genomic library was screened with a probe made from a mouse kallikrein cDNA… 
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