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Human Glandular Kallikrein 2

Known as: hK2 Kallikrein, Glandular Kallikrein 2 Precursor, Prostate Specific Kallikrein 
Kallikrein-2 (261 aa, ~29 kDa) is encoded by the human KLK2 gene. This protein plays a role in proteolysis and vasodilation.
National Institutes of Health

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14 relations
Androgen Receptor Regulation PathwayEnzyme GeneHomo sapiensHuman Glandular Kallikrein 1

Broader (1)

Tissue Kallikrein

Papers overview

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2006
2006
In silico identification and Bayesian phylogenetic analysis of multiple new mammalian kallikrein gene families.
2005
2005
Clinical utility of human glandular kallikrein 2 within a neural network for prostate cancer detection
To assess, using artificial neural networks (ANNs), human glandular kallikrein 2 (hK2), prostate‐specific antigen (PSA), and… 
2003
2003
Standardization of two immunoassays for human glandular kallikrein 2.
BACKGROUND Measurement of human kallikrein 2 (hK2) has improved early detection and staging of prostate cancer. However, reported… 
2002
2002
Preoperative blood reverse transcriptase-PCR assays for prostate-specific antigen and human glandular kallikrein for prediction of prostate cancer progression after radical prostatectomy.
The association of the results reverse transcription-PCR (RT-PCR) assays for prostate-specific antigen (PSA) with prostate cancer… 
2000
2000
An androgen response element mediates LNCaP cell dependent androgen induction of the hK2 gene
1999
1999
Human Glandular Kallikrein 2
Human glandular kallikrein 2 (hK2) is a serine protease, which is predominantly expressed by the prostate gland and found in… 
Highly Cited
1998
Highly Cited
1998
Detection of human glandular kallikrein, hK2, as its precursor form and in complex with protease inhibitors in prostate carcinoma serum.
Forms of human glandular kallikrein (kK2) in prostate carcinoma serum were identified using monoclonal antibodies specific for… 
1998
1998
alpha2-macroglobulin and C1-inactivator are plasma inhibitors of human glandular kallikrein.
Human glandular kallikrein (hK2) is a possible new marker for prostate cancer that is homologous to prostate specific antigen… 
Highly Cited
1997
Highly Cited
1997
Detection of a prostate-specific protein, human glandular kallikrein (hK2), in sera of patients with elevated prostate-specific antigen levels.
Review
1994
Review
1994
Prostate-specific antigen and human glandular kallikrein: two kallikreins of the human prostate.
Prostate-specific antigen (PSA) is a 33 kD protein synthesized in the epithelial cells of the prostate gland. It is a serine… 
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