Human Glandular Kallikrein 2

Known as: hK2 Kallikrein, Glandular Kallikrein 2 Precursor, Prostate Specific Kallikrein 
Kallikrein-2 (261 aa, ~29 kDa) is encoded by the human KLK2 gene. This protein plays a role in proteolysis and vasodilation.
National Institutes of Health

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1969-2017
010203019692017

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14 relations
Androgen Receptor Regulation PathwayEnzyme GeneHomo sapiensHuman Glandular Kallikrein 1
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Related mentions per year

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1936-2019
19401960198020002020
Human Glandular Kallikrein 2
Prostate carcinoma
Proteolysis
Tumor Markers
Homo sapiens
Tissue Kallikrein

Papers overview

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2006
2006
Serum human glandular kallikrein 2 (hK2) for distinguishing stage and grade of prostate cancer.
BACKGROUND Human glandular kallikrein (hK2) has been shown to add important information regarding the early detection and staging… (More)
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2006
2006
Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug.
BACKGROUND Prostate cancer cells secrete unique proteases such as prostate-specific antigen (PSA) and human glandular kallikrein… (More)
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2000
2000
Sensitive and specific immunodetection of human glandular kallikrein 2 in serum.
BACKGROUND Human glandular kallikrein 2 (hK2) is expressed in the prostate and is present in serum from men with prostate cancer… (More)
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2000
2000
Decreased concentrations of prostate-specific antigen and human glandular kallikrein 2 in malignant versus nonmalignant prostatic tissue.
OBJECTIVES To study quantitatively the relative expression of human glandular kallikrein 2 (hK2) and prostate-specific antigen… (More)
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1999
1999
Use of human glandular kallikrein 2 for the detection of prostate cancer: preliminary analysis.
OBJECTIVES Human glandular kallikrein 2 (hK2) and prostate-specific antigen (PSA) are members of a multigene family of serine… (More)
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1999
1999
Human glandular kallikrein 2 expression in prostate adenocarcinoma and lymph node metastases.
OBJECTIVES To describe the expression of a potential new tumor marker, human glandular kallikrein 2 (hK2), in primary… (More)
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1999
1999
Measurement of prostate-specific antigen and human glandular kallikrein 2 in different body fluids.
It has been demonstrated that prostate-specific antigen (PSA), in spite of its name, can be detected in body fluids and tumors… (More)
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1999
1999
Highly sensitive automated chemiluminometric assay for measuring free human glandular kallikrein-2.
BACKGROUND Human glandular kallikrein (hK2) is a serine protease that has 79% amino acid identity with prostate-specific antigen… (More)
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Highly Cited
1997
Highly Cited
1997
Activation of the zymogen form of prostate-specific antigen by human glandular kallikrein 2.
Prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) are glandular kallikreins secreted by the prostate gland… (More)
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Highly Cited
1997
Highly Cited
1997
Human glandular kallikrein 2 (hK2) expression in prostatic intraepithelial neoplasia and adenocarcinoma: a novel prostate cancer marker.
OBJECTIVES We describe the expression of a potentially new tumor marker, human glandular kallikrein 2 (hK2), that may be useful… (More)
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