Tissue Kallikrein

Known as: Tissue Kallikreins, Human Glandular Kallikrein, Kallikrein, Tissue 
The glandular kallikrein gene family comprises 25-30 homologous genes that encode specific proteases involved in the processing of biologically… (More)
National Institutes of Health

Related topics

Related topics

31 relations
CoagulantsEnzyme GeneHydrolysisIn Blood
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Narrower (11)

Human Glandular Kallikrein 1Human Glandular Kallikrein 2KininogensNico-Padutin
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Broader (2)

KininogenaseSerine Endopeptidases

Papers overview

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Highly Cited
2006
Highly Cited
2006
Proteinase-activated receptors, targets for kallikrein signaling.
Serine proteinases like thrombin can signal to cells by the cleavage/activation of proteinase-activated receptors (PARs… (More)
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Highly Cited
2006
Highly Cited
2006
A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation.
Desquamation of the stratum corneum is a serine protease-dependent process. Two members of the human tissue kallikrein (KLK… (More)
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Highly Cited
2006
Highly Cited
2006
A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1--the tissue kallikrein--and 14 related serine… (More)
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Review
2004
Review
2004
The emerging roles of human tissue kallikreins in cancer
Human tissue kallikreins (hKs), which are encoded by the largest contiguous cluster of protease genes in the human genome, are… (More)
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Review
2004
Review
2004
Human tissue kallikreins: physiologic roles and applications in cancer.
Tissue kallikreins are members of the S1 family (clan SA) of trypsin-like serine proteases and are present in at least six… (More)
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Review
2004
Review
2004
The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers.
Prostate specific antigen (PSA) or human kallikrein 3 (hK3) has long been an effective biomarker for prostate cancer. Now, other… (More)
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Review
2002
Review
2002
Human tissue kallikreins: a family of new cancer biomarkers.
Kallikreins are a subgroup of the serine protease enzyme family. Until recently, it was thought that the human kallikrein gene… (More)
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Highly Cited
2001
Highly Cited
2001
Local delivery of human tissue kallikrein gene accelerates spontaneous angiogenesis in mouse model of hindlimb ischemia.
BACKGROUND Human tissue kallikrein (HK) releases kinins from kininogen. We investigated whether adenovirus-mediated HK gene… (More)
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Highly Cited
2000
Highly Cited
2000
New nomenclature for the human tissue kallikrein gene family.
What do you do to start reading new nomenclature for the human tissue kallikrein gene family technical briefs? Searching the book… (More)
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Highly Cited
1987
Highly Cited
1987
Detection of tissue kallikrein in the bronchoalveolar lavage fluid of asthmatic subjects.
Kininogenase activity was detected by cleavage of radiolabeled substrate (125I-high molecular weight kininogen [HMWK]) in 22 of… (More)
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