Homology Modeling

An approach to modeling a protein structure based on an initial sequence alignment to a protein with a known 3D structure. After evaluating and… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
A correct alignment is an essential requirement in homology modeling. Yet in order to bridge the structural gap between template… (More)
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Highly Cited
2008
Highly Cited
2008
Homology modeling aims to build three-dimensional protein structure models using experimentally determined structures of related… (More)
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Highly Cited
2006
Highly Cited
2006
In this study, we investigate the extent to which techniques for homology modeling that were developed for water-soluble proteins… (More)
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Highly Cited
2005
Highly Cited
2005
Modeling a protein structure based on a homologous structure is a standard method in structural biology today. In this process an… (More)
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Highly Cited
2005
Highly Cited
2005
In this paper, we describe homology modeling of the alpha1A receptor based on the X-ray structure of bovine rhodopsin. The… (More)
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Highly Cited
2004
Highly Cited
2004
Major intrinsic proteins (MIPs) are a family of membrane channels that facilitate the bidirectional transport of water and small… (More)
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Highly Cited
2003
Highly Cited
2003
We participated in the fold recognition and homology sections of CASP5 using primarily in-house software. The central feature of… (More)
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Review
2003
Review
2003
The ultimate goal of protein modeling is to predict a structure from its sequence with an accuracy that is comparable to the best… (More)
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Highly Cited
2002
Highly Cited
2002
Homology modeling of the alpha-subunit of Na+K+-ATPase, a representative member of P-type ion transporting ATPases, was carried… (More)
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Highly Cited
1997
Highly Cited
1997
Modeling by homology is the most accurate computational method for translating an amino acid sequence into a protein structure… (More)
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