Histone H3

Known as: H3 
Histone H3 is a core subunit of the eukaryotic nucleosome complex. Histones are basic nuclear proteins responsible for the nucleosome structure of… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Mammals use DNA methylation for the heritable silencing of retrotransposons and imprinted genes and for the inactivation of the X… (More)
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Highly Cited
2007
Highly Cited
2007
Many genes associated with CpG islands undergo de novo methylation in cancer. Studies have suggested that the pattern of this… (More)
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Highly Cited
2004
Highly Cited
2004
The mechanisms by which eukaryotic cells sense DNA double-strand breaks (DSBs) in order to initiate checkpoint responses are… (More)
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Highly Cited
2002
Highly Cited
2002
Eukaryotic heterochromatin is characterized by a high density of repeats and transposons, as well as by modified histones, and… (More)
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Highly Cited
2002
Highly Cited
2002
Enhancer of Zeste is a Polycomb Group protein essential for the establishment and maintenance of repression of homeotic and other… (More)
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Highly Cited
2002
Highly Cited
2002
Gene silencing in eukaryotes is associated with the formation of heterochromatin, a complex of proteins and DNA that block… (More)
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Highly Cited
2001
Highly Cited
2001
Heterochromatin protein 1 (HP1) is localized at heterochromatin sites where it mediates gene silencing. The chromo domain of HP1… (More)
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Highly Cited
2001
Highly Cited
2001
DNA methylation is involved in epigenetic processes such as X-chromosome inactivation, imprinting and silencing of transposons… (More)
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Highly Cited
2000
Highly Cited
2000
The organization of chromatin into higher-order structures influences chromosome function and epigenetic gene regulation. Higher… (More)
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Highly Cited
1997
Highly Cited
1997
We have generated and characterized a novel site-specific antibody highly specific for the phosphorylated form of the amino… (More)
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