Hereditary pancreatitis

Known as: PANCREATITIS, CHRONIC, HP, HPC 
A disorder characterized by recurrent episodes of pancreatitis that start at a young age. It is caused by mutations in the PRSS1 or SPINK1 genes… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-2017
020406019502016

Papers overview

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Highly Cited
2008
Highly Cited
2008
Chronic pancreatitis is a persistent inflammatory disease of the pancreas, in which the digestive protease trypsin has a… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND AND AIMS:An increased risk of pancreatic adenocarcinoma (PA) in patients with hereditary pancreatitis (HP) was… (More)
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Highly Cited
2006
Highly Cited
2006
Hereditary pancreatitis has been reported to be caused by 'gain-of-function' missense mutations in the cationic trypsinogen gene… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Hereditary pancreatitis is an autosomal dominant disease that is mostly caused by cationic trypsinogen (PRSS1… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND & AIMS Nonalcoholic chronic pancreatitis is usually idiopathic and often associated with cystic fibrosis gene (CFTR… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS Gain-of-function trypsin mutations cause acute pancreatitis and chronic pancreatitis. Loss of trypsin inhibitor… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS In pancreatitis, a key role has been attributed to the inappropriate conversion of trypsinogen to trypsin… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS We recently identified a single R117H mutation in the cationic trypsinogen gene in several kindreds with an… (More)
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Highly Cited
1996
Highly Cited
1996
Hereditary pancreatitis (HP) is a rare, early-onset genetic disorder characterized by epigastric pain and often more serious… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS Hereditary pancreatitis (HP) is an autosomal-dominant disorder with incomplete penetrance characterized by… (More)
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