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Hepatocyte Nuclear Factor 4
Known as:
Hepatocyte Nuclear Factor Forkhead Homolog 4
, Hepatocyte Nuclear Factor 4 [Chemical/Ingredient]
, HNF4 Transcription Factor
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A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION…
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National Institutes of Health
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Related topics
Related topics
11 relations
HNF4A gene
In Blood
Process of secretion
agonists
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Narrower (2)
HNF4A protein, human
Hepatocyte Nuclear Factor 4-alpha
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Hepatocyte Nuclear Factor 4 Alpha Promotes Definitive Endoderm Differentiation from Human Induced Pluripotent Stem Cells
Morifumi Hanawa
,
Kazuo Takayama
,
F. Sakurai
,
M. Tachibana
,
H. Mizuguchi
Stem Cell Reviews and Reports
2016
Corpus ID: 255444986
Hepatocyte nuclear factor 4 alpha (HNF4α) is a key transcription factor for liver development. Although HNF4α is necessary for…
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2015
2015
Global gene expression changes in liver following hepatocyte nuclear factor 4 alpha deletion in adult mice
S. Gunewardena
,
Chad M. Walesky
,
U. Apte
Genomics Data
2015
Corpus ID: 12348515
2013
2013
Regulation of Apolipoprotein C-III Gene Expression by Nuclear Receptors Hepatocyte Nuclear Factor 4 Alpha and Chicken Ovalbumin Upstream Promoter Transcription Factor II, but not Retinoids in Hepatic…
M. Howell
2013
Corpus ID: 54936388
Retinoic acid (RA) treatment induces hyperlipidemia in humans and animals. RA regulates the expression levels of various genes…
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2012
2012
Pgc-1␣ Has Recently Emerged Homocysteine as a Cause of Ischemic Heart Disease: the Door Remains Open
Jean-Christophe Deschemin
,
M. Foretz
,
B. Viollet
,
S. Vaulont
2012
Corpus ID: 16005501
as an important regulator of several liver functions. In the hepatic response to fasting, PGC-1 has been shown to coordinate the…
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2004
2004
Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I.
J. Ulvila
,
Satu Arpiainen
,
+4 authors
J. Hakkola
Biochemical Journal
2004
Corpus ID: 28947983
The cytochrome P4502a5 (Cyp2a5) gene is expressed principally in liver and olfactory mucosa. In the present study, the…
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1999
1999
Extinction of alpha1-antitrypsin expression in cell hybrids is independent of HNF1alpha and HNF4 and involves both promoter and internal DNA sequences.
G. Bulla
Nucleic Acids Research
1999
Corpus ID: 40897961
In rat hepatoma x fibroblast somatic cell hybrids, extinction of rat alpha1-antitrypsin (alpha1AT) gene expression is accompanied…
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1997
1997
Proposed mechanism for the stabilization of nuclear receptor DNA binding via protein dimerization
Guoqiang Jiang
,
Una Lee
,
F. Sladek
Molecular and Cellular Biology
1997
Corpus ID: 25470457
Hepatocyte nuclear factor 4 (HNF-4) defines a new subgroup of nuclear receptors that exist in solution and bind DNA exclusively…
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1997
1997
Regulation of apolipoprotein A-I gene expression in Hep G2 cells depleted of Cu by cupruretic tetramine.
John Y. J. Wu
,
Jin J. Zhang
,
+4 authors
K. Lei
American Journal of Physiology - Cell Physiology
1997
Corpus ID: 4385810
Studies were designed to examine the regulation of apolipoprotein (apo) A-I gene expression in Cu-depleted Hep G2 cells. The…
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1997
1997
Regulation of apolipoprotein A-I gene expression in Hep G2 cells depleted of Cu by cupruretic tetramine.
J. Wu
,
J. J. Zhang
,
+4 authors
K. Lei
American Journal of Physiology
1997
Corpus ID: 25557512
Studies were designed to examine the regulation of apolipoprotein (apo) A-I gene expression in Cu-depleted Hep G2 cells. The…
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1996
1996
Regions Flanking Exon 1 Regulate Constitutive Expression of the Human Antithrombin Gene*
F. Fernandez-Rachubinski
,
J. Weiner
,
M. Blajchman
Journal of Biological Chemistry
1996
Corpus ID: 25485377
We have identified cis-acting elements and trans-acting factors that regulate constitutive expression of the human antithrombin…
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