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Hepatocyte Nuclear Factor 4
Known as:
Hepatocyte Nuclear Factor Forkhead Homolog 4
, Hepatocyte Nuclear Factor 4 [Chemical/Ingredient]
, HNF4 Transcription Factor
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A subfamily of nuclear receptors that regulate GENETIC TRANSCRIPTION of a diverse group of GENES involved in the synthesis of BLOOD COAGULATION…
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National Institutes of Health
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Related topics
Related topics
11 relations
HNF4A gene
In Blood
Process of secretion
agonists
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Narrower (2)
HNF4A protein, human
Hepatocyte Nuclear Factor 4-alpha
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila
Rebecca A. S. Palu
,
C. Thummel
PLoS Genetics
2016
Corpus ID: 34764724
SIRT1 is a member of the sirtuin family of NAD+-dependent deacetylases, which couple cellular metabolism to systemic physiology…
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2007
2007
Gene expression profiling in livers of mice after acute inhibition of beta-oxidation.
F. R. van der Leij
,
V. Bloks
,
+6 authors
F. Kuipers
Genomics
2007
Corpus ID: 4801237
2006
2006
Regulation of Mouse Hepatic α-Amino-β-Carboxymuconate-ϵ-Semialdehyde Decarboxylase, a Key Enzyme in the Tryptophan-Nicotinamide Adenine Dinucleotide Pathway, by Hepatocyte Nuclear Factor 4α and…
M. Shin
,
Insook Kim
,
Y. Inoue
,
S. Kimura
,
F. Gonzalez
Molecular Pharmacology
2006
Corpus ID: 10414479
Nicotinamide adenine dinucleotide (NAD) plays a critical role in the maintenance of cellular energy homeostasis. α-Amino…
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Highly Cited
2005
Highly Cited
2005
Transcriptional down-regulation through nuclear exclusion of EWS methylated by PRMT1.
N. Araya
,
H. Hiraga
,
K. Kako
,
Y. Arao
,
S. Kato
,
A. Fukamizu
Biochemical and Biophysical Research…
2005
Corpus ID: 20836093
Highly Cited
2002
Highly Cited
2002
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.
Francisco Valdés
,
A. Álvarez
,
+6 authors
I. Fabregat
Molecular Cancer Research
2002
Corpus ID: 261298151
Fetal rat hepatocytes treated with transforming growth factor beta (TGF-beta) die by apoptosis. However, a subpopulation of them…
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Highly Cited
2001
Highly Cited
2001
Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus‐mediated antisense targeting
R. Jover
,
R. Bort
,
M. Gómez‐Lechón
,
J. Castell
Hepatology
2001
Corpus ID: 22113270
Hepatocyte nuclear factor 4 (HNF4) is a member of the nuclear receptor super‐family that has shown activating effects on…
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Highly Cited
1998
Highly Cited
1998
SRC-1 and GRIP1 Coactivate Transcription with Hepatocyte Nuclear Factor 4*
Jen-Chywan Wang
,
J. Stafford
,
D. Granner
Journal of Biological Chemistry
1998
Corpus ID: 39198257
Hepatocyte nuclear factor-4 (HNF4), a member of the nuclear receptor superfamily, plays an important role in tissue-specific gene…
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Highly Cited
1998
Highly Cited
1998
DNA binding and transcription activation specificity of hepatocyte nuclear factor 4.
James D. Fraser
,
Verónica Martinez
,
Rose Straney
,
Michael R. Briggs
Nucleic Acids Research
1998
Corpus ID: 15136221
Hepatocyte nuclear factor 4 (HNF-4) is an orphan intracellular receptor that appears to be a key factor in the regulation of…
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Highly Cited
1997
Highly Cited
1997
Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells
Gerald F. Späth
,
Mary C. Weiss
Molecular and Cellular Biology
1997
Corpus ID: 27525490
The capacity of the liver-enriched transcription factor hepatocyte nuclear factor 4 (HNF4) to direct redifferentiation of…
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Highly Cited
1994
Highly Cited
1994
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
W. Zhong
,
J. Mirkovitch
,
J. Darnell
Molecular and Cellular Biology
1994
Corpus ID: 2769269
Hepatocyte nuclear factor 4 (HNF-4) is a liver-enriched transcription factor and a member of the steroid hormone receptor…
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