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Hepatitis C virus

Known as: human hepatitis virus C HCV, human hepatitis C virus HCV, human hepatitis C virus 
Six clades of the virus exist. But all are considered one species, since serotyping is not yet possible and they do not contain any other taxonomic… 
National Institutes of Health

Related topics

Related topics

30 relations
CDISC SDTM Microorganism TerminologyCDISC SDTM Species TerminologyClinical Data Interchange Standards Consortium TerminologyHepatitis

Broader (3)

FlaviviridaeHepatitis C-Like VirusesHepatitis Viruses

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Interplay between NS3 protease and human La protein regulates translation-replication switch of Hepatitis C virus
HCV NS3 protein plays a central role in viral polyprotein processing and RNA replication. We demonstrate that the NS3 protease… 
Highly Cited
2006
Highly Cited
2006
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras.
Chronic liver disease caused by infection with hepatitis C virus (HCV) is an important global health problem that currently… 
Highly Cited
2004
Highly Cited
2004
An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection
The CD4+CD25+ regulatory T lymphocytes have been implicated in suppressing T cell immune responses. Our aim was to characterize… 
Highly Cited
2003
Highly Cited
2003
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
Hepatitis C virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected… 
Highly Cited
2003
Highly Cited
2003
Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon.
BACKGROUND & AIMS Although the hepatitis C virus (HCV) subgenomic replicon system has been widely used in the study of HCV, this… 
Highly Cited
2003
Highly Cited
2003
Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes
Persistent infection of hepatitis C virus (HCV) is a major cause of liver diseases such as chronic hepatitis, liver cirrhosis… 
Highly Cited
2001
Highly Cited
2001
Hepatitis C virus replication in mice with chimeric human livers
Lack of a small animal model of the human hepatitis C virus (HCV) has impeded development of antiviral therapies against this… 
Highly Cited
2001
Highly Cited
2001
Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus
ABSTRACT Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is likely that, as with other… 
Highly Cited
1999
Highly Cited
1999
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
Various classes of nucleotidyl polymerases with different transcriptional roles contain a conserved core structure. Less is known… 
Highly Cited
1991
Highly Cited
1991
Genetic organization and diversity of the hepatitis C virus.
The nucleotide sequence of the RNA genome of the human hepatitis C virus (HCV) has been determined from overlapping cDNA clones… 
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