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Hep G2 Cells

Known as: HepG2 Cell, Cell, HepG2, Hepatoblastoma G2 Cell Line 
A human liver tumor cell line used to study a variety of liver-specific metabolic functions.
National Institutes of Health

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MicrobiologicalProcess of secretionaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2010
Highly Cited
2010
The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the…
Highly Cited
2008
Highly Cited
2008
Development and properties of HepG2 cells that constitutively express CYP2E1.
CYP2E1, a member of the cytochrome P450 family, is induced by ethanol. CYP2E1 activates many hepatotoxins to their reactive toxic… 
Highly Cited
2006
Highly Cited
2006
Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells
There is an ongoing controversy regarding the relevance of apoptosis induction by ionizing irradiation as compared with other end… 
Highly Cited
2005
Highly Cited
2005
Glucocorticoid receptor isoforms in human hepatocarcinoma HepG2 and SaOS-2 osteosarcoma cells: presence of glucocorticoid receptor alpha in mitochondria and of glucocorticoid receptor beta in…
Highly Cited
2002
Highly Cited
2002
Three-point functions of N=4 super-Yang–Mills from light cone string field theory in pp-wave
Highly Cited
2000
Highly Cited
2000
Selective transcriptional regulations in the human liver cell by hepatitis B viral X protein.
The hepatitis B viral X protein (HBx) is known as a transcription factor and potential oncogene. To gain a better view of the… 
Highly Cited
2000
Highly Cited
2000
Quantitative analysis of constitutive and inducible CYPs mRNA expression in the HepG2 cell line using reverse transcription-competitive PCR.
Drug interactions which affect drug metabolism are of clinical importance. It is, however, difficult to estimate drug… 
Highly Cited
1999
Highly Cited
1999
Cytokines, growth factors, and oxidative stress in HepG2 cells treated with ethanol, acetaldehyde, and LPS.
Highly Cited
1997
Highly Cited
1997
Norcantharidin inhibits growth of human HepG2 cell-transplanted tumor in nude mice and prolongs host survival.
Highly Cited
1990
Highly Cited
1990
Insulin regulation of hexose transport in mouse 3T3-L1 cells expressing the human HepG2 glucose transporter.
Complementary DNA encoding a HepG2 cell-facilitated glucose transporter (GLUT1) was subcloned into a metal-inducible, mammalian… 
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