Skip to search formSkip to main contentSkip to account menu

Hemophilia B

Known as: Deficiency, plasma thromboplastin component, Deficiency, functional factor IX, Deficiency, PTC 
A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in… 
National Institutes of Health

Related topics

Related topics

33 relations

Broader (2)

Blood Coagulation DisordersHereditary Diseases
Danaparoid sodiumDicumarolF9 geneF9 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
Knee arthroplasty in hemophilic arthropathy.
Twenty-three total knee arthroplasties in 15 patients with severe hemophilia were performed between February 1974 and September… 
Highly Cited
1994
Highly Cited
1994
Haemophilia A diagnosis by simultaneous analysis of two variable dinucleotide tandem repeats within the factor VIII gene
Summary. Haemophilia A is a bleeding disorder caused by defects in the gene coding for the co‐factor, factor VIII (FVIII). The… 
Highly Cited
1992
Highly Cited
1992
Disruption of a binding site for hepatocyte nuclear factor 4 results in hemophilia B Leyden.
Hemophilia B Leyden is an X chromosome-linked bleeding disorder characterized by very low plasma levels of blood coagulation… 
Highly Cited
1990
Highly Cited
1990
Haemophilia B: database of point mutations and short additions and deletions, 7th edition
The seventh edition of the haemophilia B database lists in easily accessible form all known factor IX mutations due to small… 
Highly Cited
1990
Highly Cited
1990
Mutations causing hemophilia B: direct estimate of the underlying rates of spontaneous germ-line transitions, transversions, and deletions in a human gene.
Spontaneous mutation provides the substrate for evolution on one hand and for genetic susceptibility to disease on the other hand… 
Highly Cited
1990
Highly Cited
1990
Medical geneticists confront ethical dilemmas: cross-cultural comparisons among 18 nations.
To provide a basis for international discussion of ethical problems, we studied responses of medical geneticists in 18 countries… 
Highly Cited
1989
Highly Cited
1989
Mutations in the catalytic domain of human coagulation factor IX: rapid characterization by direct genomic sequencing of DNA fragments displaying an altered melting behavior.
Highly Cited
1988
Highly Cited
1988
The putative factor IX gene promoter in hemophilia B Leyden.
Hemophilia B Leyden is characterized by low levels of factor IX antigen and activity before the age of 15, whereas after puberty… 
Highly Cited
1984
Highly Cited
1984
ANTIBODY TO LYMPHADENOPATHY-ASSOCIATED VIRUS IN HAEMOPHILIACS WITH AND WITHOUT AIDS
Highly Cited
1969
Highly Cited
1969
Treatment of hemophilia B with a new clotting-factor concentrate.
Abstract A new concentrate of clotting factors II, VII, IX and X, made from pooled human plasma collected in citrate… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)