Skip to search formSkip to main contentSkip to account menu

Heavy Chain Disease

Known as: BALLARD DISEASE, HCD, Heavy Chain Disease [Disease/Finding] 
A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the… 
National Institutes of Health

Related topics

Related topics

30 relations
Atypical lymphocyteB lymphoblastB-LymphocytesDIH1 gene

Narrower (4)

Immunoproliferative Small Intestinal DiseaseRIV immunoglobulin variant protein, humanWis heavy-chain disease protein, humanmu-Chain Disease

Broader (1)

gammopathy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Improvement of Ca balance by Fructus Ligustri Lucidi extract in aged female rats
SummaryThis study aimed to demonstrate and delineate the mechanism of action of Fructus Ligustri Lucidi (FLL) involved in… 
2005
2005
Low-grade B-Cell lymphomas with plasmacytic differentiation lack PAX5 gene rearrangements.
2002
2002
Effect of macronutrient composition of the diet on the regulation of lipolysis in adipose tissue at rest and during exercise: microdialysis study.
The aim of the present study was to elucidate, using a microdialysis technique, whether modifications in the proportion of fat in… 
1981
1981
Two alpha heavy chain disease proteins with different genomic deletions demonstrate that nonexpressed alpha heavy chain genes contain methylated bases.
Two independently arising alpha heavy chain mutants have been found to synthesize heavy chains with CH1 deletions of… 
1972
1972
Molecular Defect in a Gamma-2 (γ2) Heavy Chain
The first gamma-2 (γ2) heavy chain disease protein Gif has pyrroli-dinecarboxylic acid as its amino terminal residue, much of the… 
1972
1972
Alpha and gamma heavy chain diseases in man: intracellular origin of the aberrant polypeptides.
Immunofluorescent and in vitro labeling studies were carried out on cells obtained from patients with α and γ heavy chain… 
1971
1971
Alpha heavy chain disease. A variant of Mediterranean lymphoma.
The Mediterranean type of abdominal lymphoma has recently been described as a separate disease entity by Ramot et al, 1 Eidelman… 
1970
1970
Implications of heavy chain disease protein sequences for multiple gene theories of immunoglobulin synthesis.
The sequence of the amino-terminal 34 amino acids of gamma-heavy chain disease (gamma-HCD) protein Hi is homologous with the… 
Highly Cited
1969
Highly Cited
1969
Partial Deletion in the Heavy Chain Disease Protein ZUC
HEAVY chain disease1,2 is characterized by the presence in serum and urine of a protein associated structurally with the Fc… 
1967
1967
N-and C-terminal Sequences of a Heavy Chain Disease Protein and its Genetic Implications
A VARIANT of myeloma has been described1,2; it is known as heavy chain disease, and is characterized by the presence of a… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)