Haptens

Known as: partial antigen, Haptens [Chemical/Ingredient], haptene 
Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves… (More)

Topic mentions per year

Topic mentions per year

1935-2018
010020019352017

Papers overview

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Highly Cited
2011
Highly Cited
2011
A prominent feature of sensitizing environmental compounds that cause allergic contact dermatitis is the rapid induction of an… (More)
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Highly Cited
2010
Highly Cited
2010
Hepatic natural killer (NK) cells mediate antigen-specific contact hypersensitivity (CHS) in mice deficient in T cells and B… (More)
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Highly Cited
2007
Highly Cited
2007
Animal models of intestinal inflammation are indispensable for our understanding of the pathogenesis of Crohn disease and… (More)
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Highly Cited
2006
Highly Cited
2006
It is commonly believed that only T lymphocytes and B lymphocytes expressing recombination-dependent antigen-specific receptors… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in the NALP3/CIAS1/cryopyrin gene are linked to three autoinflammatory disorders: Muckle-Wells syndrome, familial cold… (More)
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Highly Cited
2003
Highly Cited
2003
A range of synthetic methyl hexagalacturonates were used as potential hapten inhibitors in competitive-inhibition enzyme-linked… (More)
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Highly Cited
1996
Highly Cited
1996
Contact hypersensitivity (CHS) is a T cell-mediated response to hapten sensitization of the epidermis. The roles of CD4+ and CD8… (More)
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Highly Cited
1991
Highly Cited
1991
Techniques which identify hapten-specific B cells in tissues have been used to determine the sites of B cell activation in rat… (More)
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Highly Cited
1989
Highly Cited
1989
We have developed a simple and reproducible rat model of chronic colonic inflammation by the intraluminal instillation of a… (More)
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Highly Cited
1970
Highly Cited
1970
1) Induction of humoral antibody formation involves the obligatory recognition of two determinants on an antigen, one by the… (More)
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