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Halothane Hepatitis

Known as: HEPATITIS, HALOTHANE 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Chemical and Drug Induced Liver InjuryHalothane

Papers overview

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Highly Cited
1997
Highly Cited
1997
Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons
Highly Cited
1996
Highly Cited
1996
Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis.
Autoantibodies against specific human cytochrome P450s have been found in the sera of patients suffering from a variety of… 
Review
1993
Review
1993
Mechanisms of halothane toxicity: novel insights.
Highly Cited
1990
Highly Cited
1990
Halothane Hepatitis in Children
Halothane hepatitis is now a well-recognized distinct entity in adults, but there prevails an often-taught “axiom” that halothane… 
Highly Cited
1988
Highly Cited
1988
Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane.
Previous studies have demonstrated that antibodies in sera from patients with halothane hepatitis recognize halothane-induced… 
Highly Cited
1988
Highly Cited
1988
Evidence for expression in human liver of halothane‐induced neoantigens recognized by antibodies in sera from patients with halothane hepatitis
Previous investigations have shown that antibodies in sera from patients with halothane hepatitis recognize neoantigens… 
Highly Cited
1988
Highly Cited
1988
Enflurane metabolism produces covalently bound liver adducts recognized by antibodies from patients with halothane hepatitis.
The existence of a rare syndrome of "enflurane hepatitis" similar to that described for halothane and of a cross-sensitization… 
Review
1987
Review
1987
Clinical Pharmacokinetics of the Inhalational Anaesthetics
SummaryAt present, the most widely used inhalational anaesthetics are the halogenated, inflammable vapours halothane, enflurane… 
Review
1987
Review
1987
Halothane hepatitis in children.
It is often stated that halothane hepatitis in children is nonexistent or extremely rare. This syndrome occurred in seven… 
Highly Cited
1970
Highly Cited
1970
Lymphocyte stimulation induced by halothane in patients with hepatitis following exposure to halothane.
Abstract Stimulation of lymphocytes, as measured by incorporation of 3H-thymidine into the deoxyribonucleic acid of lymphocytes… 
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