Halothane Hepatitis

Known as: HEPATITIS, HALOTHANE 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2017
051019632017

Papers overview

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2010
2010
Halothane (2-bromo-2-chloro-1,1,1-trifluoro-ethane) is an inhaled anesthetic that induces severe, idiosyncratic liver injury, i.e… (More)
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1997
1997
The volatile anesthetic halothane undergoes substantial biotransformation generating metabolites that mediate hepatotoxicity… (More)
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1997
1997
In susceptible patients, halothane, enflurane, isoflurane, and desflurane can produce severe hepatic injury by an immune response… (More)
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1996
1996
Autoantibodies against specific human cytochrome P450s have been found in the sera of patients suffering from a variety of… (More)
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1996
1996
BACKGROUND Fulminant hepatic necrosis ("halothane hepatitis") is an unusual and often fatal complication of halothane anaesthesia… (More)
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1996
1996
Recent studies have shown that cytochrome P450 2E1 (CYP2E1) is a major catalyst of formation of trifluoroacetylated proteins… (More)
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1990
1990
Halothane hepatitis is now a well-recognized distinct entity in adults, but there prevails an often-taught "axiom" that halothane… (More)
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1988
1988
Previous investigations have shown that antibodies in sera from patients with halothane hepatitis recognize neoantigens… (More)
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1988
1988
Previous studies have demonstrated that antibodies in sera from patients with halothane hepatitis recognize halothane-induced… (More)
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1985
1985
We studied susceptibility to halothane hepatitis with an in vitro test that detects cell damage from electrophilic drug… (More)
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