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HTR2B gene

Known as: 5-HYDROXYTRYPTAMINE RECEPTOR 2B, 5-HT(2B), 5-HT2B 
National Institutes of Health

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Related topics

2 relations
HTR1B geneReceptor, Serotonin, 5-HT2B

Papers overview

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Highly Cited
2018
Highly Cited
2018
Positive regulation of raphe serotonin neurons by serotonin 2B receptors
Serotonin is a neurotransmitter involved in many psychiatric diseases. In humans, a lack of 5-HT2B receptors is associated with… 
Highly Cited
2013
Highly Cited
2013
Clinical and genetic risk factors for type 2 diabetes at early or late post partum after gestational diabetes mellitus.
CONTEXT Women with a history of gestational diabetes mellitus (GDM) are at increased risk of type 2 diabetes (T2DM). However, the… 
Highly Cited
2012
Highly Cited
2012
Gut-derived serotonin is a multifunctional determinant to fasting adaptation.
Highly Cited
2012
Highly Cited
2012
5-HT2B receptors are required for serotonin-selective antidepressant actions
The therapeutic effects induced by serotonin-selective reuptake inhibitor (SSRI) antidepressants are initially triggered by… 
Highly Cited
2004
Highly Cited
2004
Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors
In the present study we compared the affinity of various drugs for the high affinity “agonist-preferring” binding site of human… 
Highly Cited
2003
Highly Cited
2003
Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5‐HT2B‐receptor signaling
Identification of factors regulating cardiomyocyte survival and growth is important to understand the pathogenesis of congenital… 
2003
2003
Agonist actions of dihydroergotamine at 5‐HT2B and 5‐HT2C receptors and their possible relevance to antimigraine efficacy
The pharmaceutical compound, dihydroergotamine (DHE) is dispensed to prevent and reduce the occurrence of migraine attacks… 
Highly Cited
1999
Highly Cited
1999
Comparisons of hallucinogenic phenylisopropylamine binding affinities at cloned human 5-HT2A, 5-HT2B and 5-HT2C receptors
Since the classical hallucinogens were initially reported to produce their behavioral effects via a 5-HT2 agonist mechanism (i.e… 
Highly Cited
1996
Highly Cited
1996
Activation of Meningeal 5‐HT2B Receptors: An Early Step in the Generation of Migraine Headache?
Several pharmaceuticals are frequently dispensed to prevent or reduce the occurrence of migraine attacks. The prophylactic effect… 
Highly Cited
1995
Highly Cited
1995
5-Methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole: a novel 5-HT2C/5-HT2B receptor antagonist with improved affinity, selectivity, and oral activity.
The preparation of a series of conformationally restricted analogues of indolylurea 1, namely tetrahydropyrroloindoles and… 
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