Receptor, Serotonin, 5-HT2B

Known as: (5-HT)2B Receptors, Receptor, 5-HT2B, 5 Hydroxytryptamine 2B Receptor 
A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs. A number of functions have been attributed to… (More)
National Institutes of Health

Related topics

Related topics

4 relations
HTR2B geneIn Bloodaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
Tissue homeostasis requires an effective, limited wound-healing response to injury. In chronic disease, failure to regenerate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation
Fluoxetine has relatively high affinity for Gq/11 protein-coupled 5-HT2 receptors. Part of these receptors in brain are on… (More)
  • table 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation.
The monoamine serotonin (5-HT), a well-known neurotransmitter, is also important in peripheral tissues. Several studies have… (More)
Is this relevant?
2006
2006
Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells.
The plasma membrane 5-HT transporter (SERT) is the major protagonist in regulating extracellular 5-HT concentration and… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2003
2003
Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy.
BACKGROUND Identification of factors regulating myocardial structure and function is important to understand the pathogenesis of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Serotonin 2B receptor is required for heart development.
Several lines of evidence suggest that the serotonin (5-hydroxytryptamine, 5-HT) regulates cardiovascular functions during… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
Highly Cited
1996
Highly Cited
1996
In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties.
1. SB 206553 (5-methyl-1-(3-pyridylcarbamoyl)-1,2,3,5-tetrahydropyrrolo[2 ,3-f]indole) displays a high affinity (pK1 7.9) for the… (More)
Is this relevant?
1996
1996
Immunohistochemical localisation of the serotonin 5-HT2B receptor in mouse gut, cardiovascular system, and brain.
We recently reported the cloning of a new member of the serotonin 5-HT2 family, the 5-HT2B receptor. We now report the production… (More)
Is this relevant?
1996
1996
Ras involvement in signal transduction by the serotonin 5-HT2B receptor.
The family of serotonin 5-HT2 receptors stimulates the phospholipase C second messenger pathway via the alpha subunit of the Gq… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The pharmacology and distribution of human 5-hydroxytryptamine2B (5-HT2B) receptor gene products: comparison with 5-HT2A and 5-HT2C receptors.
1. Full length clones of the human 5-HT2B receptor were isolated from human liver, kidney and pancreas. The cloned human 5-HT2B… (More)
Is this relevant?