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Receptor, Serotonin, 5-HT2B

Known as: (5-HT)2B Receptors, Receptor, 5-HT2B, 5 Hydroxytryptamine 2B Receptor 
A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs. A number of functions have been attributed to… Expand
National Institutes of Health

Related topics

Related topics

4 relations
HTR2B geneIn Bloodaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2011
Highly Cited
2011
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
Tissue homeostasis requires an effective, limited wound-healing response to injury. In chronic disease, failure to regenerate… Expand
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Highly Cited
2008
Highly Cited
2008
The serotonin 5‐HT2B receptor controls bone mass via osteoblast recruitment and proliferation
The monoamine serotonin (5‐HT), a well‐known neurotransmitter, is also important in peripheral tissues. Several studies have… Expand
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Highly Cited
2006
Highly Cited
2006
Serotonin transport and serotonin transporter‐mediated antidepressant recognition are controlled by 5‐HT2B receptor signaling in serotonergic neuronal cells
The plasma membrane 5‐HT transporter (SERT) is the major protagonist in regulating extracellular 5‐HT concentration and… Expand
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Highly Cited
2004
Highly Cited
2004
Up-Regulation of 5-HT2B Receptor Density and Receptor-Mediated Glycogenolysis in Mouse Astrocytes by Long-Term Fluoxetine Administration
The effects were studied of short-term (1 week) versus long-term (2-3 weeks) fluoxetine treatment of primary cultures of mouse… Expand
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Highly Cited
2000
Highly Cited
2000
Serotonin 2B receptor is required for heart development.
Several lines of evidence suggest that the serotonin (5-hydroxytryptamine, 5-HT) regulates cardiovascular functions during… Expand
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Highly Cited
1997
Highly Cited
1997
5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.
During embryogenesis, serotonin has been reported to be involved in craniofacial and cardiovascular morphogenesis. The detailed… Expand
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Highly Cited
1996
Highly Cited
1996
In vitro and in vivo profile of SB 206553, a potent 5‐HT2C/5‐HT2B receptor antagonist with anxiolytic‐like properties
1 SB 206553 (5‐methyl‐1‐(3‐pyridylcarbamoyl)‐1,2,3,5‐tetrahydropyrrolo[2,3‐f]indole) displays a high affinity (pK1 7.9) for the… Expand
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Highly Cited
1995
Highly Cited
1995
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
1 Full length clones of the human 5‐HT2B receptor were isolated from human liver, kidney and pancreas. The cloned human 5‐HT2B… Expand
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Highly Cited
1994
Highly Cited
1994
In vivo properties of SB 200646A, a 5‐HT2C/2B receptor antagonist
1 SB 200646A, N‐(1‐methyl‐5‐indolyl)‐N′‐(3‐pyridyl) urea hydrochloride, the first reported selective 5‐HT2C/2B over 5‐HT2A… Expand
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Highly Cited
1994
Highly Cited
1994
Cloning and functional characterization of the human 5‐HT2B serotonin receptor
Recently, we have reported the cloning of the rat 5‐HT2B receptor cDNA. This receptor is particularly interesting since it may be… Expand
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