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Receptor, Serotonin, 5-HT2B
Known as:
(5-HT)2B Receptors
, Receptor, 5-HT2B
, 5 Hydroxytryptamine 2B Receptor
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A serotonin receptor subtype found in the BRAIN; HEART; LUNGS; PLACENTA and DIGESTIVE SYSTEM organs. A number of functions have been attributed to…
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National Institutes of Health
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Related topics
Related topics
4 relations
HTR2B gene
In Blood
aspects of radiation effects
physiological aspects
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
M. Ebrahimkhani
,
F. Oakley
,
+12 authors
D. Mann
Nature Medicine
2011
Corpus ID: 4072181
Tissue homeostasis requires an effective, limited wound-healing response to injury. In chronic disease, failure to regenerate…
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Highly Cited
2009
Highly Cited
2009
Stress Impairs 5-HT2A Receptor-Mediated Serotonergic Facilitation of GABA Release in Juvenile Rat Basolateral Amygdala
Xiaolong Jiang
,
G. Xing
,
Chunhui Yang
,
A. Verma
,
Lei Zhang
,
He Li
Neuropsychopharmacology
2009
Corpus ID: 6647462
The occurrence of stress and anxiety disorders has been closely associated with alterations of the amygdala GABAergic system. In…
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Highly Cited
2006
Highly Cited
2006
Serotonin transport and serotonin transporter‐mediated antidepressant recognition are controlled by 5‐HT2B receptor signaling in serotonergic neuronal cells
Jean‐Marie Lamiay
,
B. Schneider
,
S. Loric
,
M. Prada
,
O. Kellermann
FASEB journal : official publication of the…
2006
Corpus ID: 3163986
The plasma membrane 5‐HT transporter (SERT) is the major protagonist in regulating extracellular 5‐HT concentration and…
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Highly Cited
2004
Highly Cited
2004
Up-Regulation of 5-HT2B Receptor Density and Receptor-Mediated Glycogenolysis in Mouse Astrocytes by Long-Term Fluoxetine Administration
Ebenezer K. C. Kong
,
Liang Peng
,
Ye Chen
,
A. Yu
,
L. Hertz
Neurochemical Research
2004
Corpus ID: 23550831
The effects were studied of short-term (1 week) versus long-term (2-3 weeks) fluoxetine treatment of primary cultures of mouse…
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Highly Cited
2003
Highly Cited
2003
Overexpression of the Serotonin 5-HT2B Receptor in Heart Leads to Abnormal Mitochondrial Function and Cardiac Hypertrophy
C. Nebigil
,
Fabrice Jaffré
,
+4 authors
L. Maroteaux
Circulation
2003
Corpus ID: 13035497
Background—Identification of factors regulating myocardial structure and function is important to understand the pathogenesis of…
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Highly Cited
2000
Highly Cited
2000
Serotonin 2B receptor is required for heart development.
C. Nebigil
,
D. Choi
,
+5 authors
L. Maroteaux
Proceedings of the National Academy of Sciences…
2000
Corpus ID: 9888414
Several lines of evidence suggest that the serotonin (5-hydroxytryptamine, 5-HT) regulates cardiovascular functions during…
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Highly Cited
1997
Highly Cited
1997
5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.
D. Choi
,
S. Ward
,
N. Messaddeq
,
J. Launay
,
L. Maroteaux
Development
1997
Corpus ID: 42267175
During embryogenesis, serotonin has been reported to be involved in craniofacial and cardiovascular morphogenesis. The detailed…
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Highly Cited
1996
Highly Cited
1996
In vitro and in vivo profile of SB 206553, a potent 5‐HT2C/5‐HT2B receptor antagonist with anxiolytic‐like properties
G. Kennett
,
M. Wood
,
+8 authors
T. Blackburn
British journal of pharmacology
1996
Corpus ID: 21576168
1 SB 206553 (5‐methyl‐1‐(3‐pyridylcarbamoyl)‐1,2,3,5‐tetrahydropyrrolo[2,3‐f]indole) displays a high affinity (pK1 7.9) for the…
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Highly Cited
1995
Highly Cited
1995
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
D. Bonhaus
,
C. Bach
,
+5 authors
R. Eglen
British journal of pharmacology
1995
Corpus ID: 32554403
1 Full length clones of the human 5‐HT2B receptor were isolated from human liver, kidney and pancreas. The cloned human 5‐HT2B…
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Highly Cited
1994
Highly Cited
1994
In vivo properties of SB 200646A, a 5‐HT2C/2B receptor antagonist
G. Kennett
,
M. Wood
,
+4 authors
T. Blackburn
British journal of pharmacology
1994
Corpus ID: 19899566
1 SB 200646A, N‐(1‐methyl‐5‐indolyl)‐N′‐(3‐pyridyl) urea hydrochloride, the first reported selective 5‐HT2C/2B over 5‐HT2A…
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