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HSV-Tk Gene

Known as: HSV-Tk, Herpes Simplex Virus Thymidine Kinase Gene 
Herpes simplex virus thymidine kinase (HSV-Tk) gene encodes thymidine kinase protein, which is important for herpes simplex virus infection. The TK… 
National Institutes of Health

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PhosphorylationSimplexvirusVirus Physiological Phenomena

Papers overview

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1985
1985
Transfection of mouse fibroblast cells with a promoterless herpes simplex virus thymidine kinase gene: number of integrated gene copies and structure of single and amplified gene sequences
Plasmids carrying the herpes simplex virus thymidine kinase (tk) gene were used to transfect thymidine kinase-deficient cells of… 
1985
1985
Isolation of cis-acting vaccinia virus DNA fragments promoting the expression of herpes simplex virus thymidine kinase by recombinant viruses
Recombinant TK- vaccinia viruses containing the pBR322 sequence inserted in either orientation within the coding sequence of the… 
1985
1985
Identification of sequences in the herpes simplex virus thymidine kinase gene required for efficient processing and polyadenylation
The herpes simplex virus (HSV) type 1 thymidine kinase gene (tk) was resected from its 3' end with BAL 31 exonuclease. Two sets… 
1984
1984
Expression in COS-1 cells of Epstein-Barr virus nuclear antigen from a complete gene and a deleted gene
In a previous study the BamHI-K fragment of Epstein-Barr virus DNA was shown to induce a nuclear antigen, Epstein-Barr virus… 
1984
1984
Use of the mouse mammary tumor virus long terminal repeat to promote steroid-inducible expression of v-mos
We used the mouse mammary tumor virus long terminal repeat to promote dexamethasone-regulated expression of the Moloney murine… 
1983
1983
Positive control of the herpes simplex virus thymidine kinase gene requires upstream DNA sequences
We examined the ability of deleted versions of the herpes simplex virus type 1 thymidine kinase gene, present in biochemically… 
1983
1983
Functional suppression in mammalian cells of nonsense mutations in the herpes simplex virus thymidine kinase gene by suppressor tRNA genes
A nonsense mutation (UAG) in the thymidine kinase gene of herpes simplex virus type 1 can be suppressed in vivo to produce active… 
1982
1982
Retrovirus long terminal repeats activate expression of coding sequences for the herpes simplex virus thymidine kinase gene.
In this study, we demonstrate that the long terminal repeats (LTRs) of a murine retrovirus can activate expression of… 
1979
1979
Virus-specific DNA sequences present in cells which carry the herpes simplex virus thymidine kinase gene.
Two independently derived cell lines which carry the herpes simplex type 2 thymidine kinase gene have been examined for the… 
1975
1975
Control of the expression of a herpes simplex virus thymidine kinase gene incorporated into thymidine kinase-deficient mouse cells
When thymidine kinase-deficient mouse cells “transformed” by inactivated herpes simplex virus and expressing the viral thymidine…