Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

HSV-Tk Gene

Known as: HSV-Tk, Herpes Simplex Virus Thymidine Kinase Gene 
Herpes simplex virus thymidine kinase (HSV-Tk) gene encodes thymidine kinase protein, which is important for herpes simplex virus infection. The TK… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Between December 1996 and September 1998, 13 patients with advanced recurrent malignant brain tumors (9 with glioblastoma… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
We report successful electro-gene therapy (EGT) by using plasmid DNA for tumor-bearing mice. Subcutaneously inoculated CT26 tumor… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
Highly Cited
1999
Highly Cited
1999
For patients with local recurrence of prostate cancer after definitive irradiation therapy there is no treatment widely… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND A bacterial enzyme, Escherichia coli cytosine deaminase, which converts the prodrug 5-fluorocytosine into the toxic… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
We have developed a recombinant replication‐defective adenovirus containing human α‐fetoprotein (AFP) promoter/enhancer to direct… Expand
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Of 18 mutants containing clustered point mutations within UL24 (an open reading frame that overlaps the herpes simplex virus… Expand
Is this relevant?
Highly Cited
1987
Highly Cited
1987
To define the recognition sequence of the glucocorticoid receptor and its relationship with that of the progesterone receptor… Expand
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Abstract We have studied the effect of DNA methylation on human γ-globin gene expression, using a novel in vitro DNA methylation… Expand
Is this relevant?
Highly Cited
1982
Highly Cited
1982
We have constructed recombinant vaccinia viruses containing the thymidine kinase gene from herpes simplex virus. The gene was… Expand
Is this relevant?
Highly Cited
1982
Highly Cited
1982
Previous deletion analysis of the Drosophila hsp70 heat‐shock promoter has identified a sequence upstream of the TATA box that is… Expand
Is this relevant?