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HSD17B1 gene

Known as: MGC138140, short chain dehydrogenase/reductase family 28CE, member 1, hydroxysteroid (17-beta) dehydrogenase 1 
This gene is involved in estrogen biosynthesis.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
In this study, to search for novel preeclampsia (PE) biomarkers, we focused on microRNA expression and function in the human… 
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Highly Cited
2011
Highly Cited
2011
Objective. To investigate whether polymorphisms in genes involved in biosynthesis and signalling of sex steroids influence… 
2007
2007
In situ synthesis of estrogens is believed to be of great importance for the progression of breast cancer. In postmenopausal… 
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Highly Cited
2006
Highly Cited
2006
The 17beta-hydroxysteroid dehydrogenase 1 gene (HSD17B1) encodes 17HSD1, which catalyzes the final step of estradiol biosynthesis… 
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Highly Cited
2005
Highly Cited
2005
Steroid hormones are believed to play an important role in prostate carcinogenesis, but epidemiological evidence linking prostate… 
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Highly Cited
2004
Highly Cited
2004
Estrogen exposure influences breast and endometrial cancer risk. The HSD17B1 gene produces an enzyme that catalyzes the… 
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Highly Cited
2003
Highly Cited
2003
Estrogens play a crucial role in the development of breast cancer. Estradiol can be produced in the breast tissue in situ, and… 
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Highly Cited
2001
Highly Cited
2001
We conducted a nested case-control study to evaluate whether polymorphisms in two genes involved in estrogen metabolism, CYP17… 
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1997
1997
Human 17β-hydroxysteroid dehydrogenase type 1 (17HSD type 1) primarily catalyzes the reduction of low activity estrone to high… 
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Highly Cited
1977
Highly Cited
1977
The Raleigh, North Carolina, population of Drosophila melanogaster was examined for linkage disequilibrium in 1974, several years… 
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