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HSD17B1 protein, human

Known as: Short Chain Dehydrogenase/Reductase Family 28CE, Member 1, Estradiol 17-Beta-Dehydrogenase 1, 17-Beta-HSD I 
Estradiol 17-beta-dehydrogenase 1 (328 aa, ~35 kDa) is encoded by the human HSD17B1 gene. This protein is involved in the conversion of both… Expand
National Institutes of Health

Related topics

Related topics

7 relations
20-alpha-Hydroxysteroid DehydrogenaseEnzyme GeneEstradiol 17 beta-DehydrogenaseHSD17B1 gene
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Broader (1)

Estradiol Dehydrogenases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
17β‐hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone‐dependent breast cancer
Oestradiol (E2) stimulates the growth of hormone‐dependent breast cancer. 17β‐hydroxysteroid dehydrogenases (17β‐HSDs) catalyse… Expand
Highly Cited
2008
Highly Cited
2008
Rapid estrogen regulation of DHEA metabolism in the male and female songbird brain
In the songbird brain, dehydroepiandrosterone (DHEA) is metabolized to the active and aromatizable androgen androstenedione (AE… Expand
Review
2008
Review
2008
Emerging roles for neurosteroids in sexual behavior and function.
  • S. King
  • Journal of andrology
  • 2008
    • Corpus ID: 8834769
Although gonadal and adrenal steroids heavily impact sexual function at the level of the brain, the nervous system also produces… Expand
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2004
2004
Expression of 17beta- and 3beta-hydroxysteroid dehydrogenases and steroidogenic acute regulatory protein in non-luteinizing bovine granulosa cells in vitro.
Granulosa cells of small follicles differentiate in vitro in serum-free medium, resulting in increased estradiol secretion and… Expand
1999
1999
Steroidogenic enzyme expression in human corpora lutea in the presence and absence of exogenous human chorionic gonadotrophin (HCG).
In a human conception cycle, the expected decline in progesterone production by the corpus luteum during the late luteal phase is… Expand
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1999
1999
Regulation of steroidogenesis in jc-410, a stable cell line of porcine granulosa origin
We investigated the regulation of steroidogenesis in a cell line of porcine granulosa origin, JC-410. Cells responded to the… Expand
1986
1986
The effect of epidermal growth factor, transforming growth factor and breast tumour homogenates on the activity of oestradiol 17 beta hydroxysteroid dehydrogenase in cultured adipose tissue.
The effect of epidermal growth factor (EGF), transforming growth factor (TGF alpha) and breast tumour homogenates on oestradiol… Expand
1985
1985
Estradiol 17 beta-hydroxysteroid dehydrogenase, a marker of breast cancer hormone dependency.
Intratumoral activity of the progesterone-dependent enzyme 17 beta-hydroxysteroid dehydrogenase (E2DH) was measured in 114… Expand
Highly Cited
1982
Highly Cited
1982
Estradiol 17 beta-hydroxysteroid dehydrogenase activity in human breast fibroadenomas.
In the human endometrium, the presence of the progesterone-dependent enzyme 17 beta-hydroxysteroid dehydrogenase (E2DH) permits… Expand
1982
1982
Failure of progestins to induce estradiol dehydrogenase activity in endometrial carcinoma, in vitro.
Estradiol dehydrogenase (E2DH) is a well-known progesterone-dependent enzyme in human endometrium, and its induction has been… Expand
  • table 1
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