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HPSE wt Allele

Known as: HPA, HPSE1, HEP 
Human HPSE wild-type allele is located in the vicinity of 4q21.3 and is approximately 43 kb in length. This allele, which encodes heparanase protein… 
National Institutes of Health

Related topics

Related topics

8 relations
4q21.3Angiogenic ProcessBlood coagulationCell-Matrix Junction

Broader (1)

HPSE gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Early Childbearing, Human Capital Attainment, and Mortality Risk: Evidence from a Longitudinal Demographic Surveillance Area in Rural KwaZulu-Natal, South Africa
Using a rich longitudinal data set, we examine the relationship between teen fertility and both subsequent educational outcomes… 
2007
2007
In Vivo and in Vitro Degradation of Heparan Sulfate (HS) Proteoglycans by HPR1 in Pancreatic Adenocarcinomas
Heparan sulfate proteoglycans (HSPGs) function as a co-receptor for heparin-binding growth factors, such as fibroblast growth… 
Highly Cited
2006
Highly Cited
2006
Elevated serum heparanase‐1 levels in patients with pancreatic carcinoma are associated with poor survival
It has previously been shown that heparanase‐1 (HPR1), an endoglycosidase, is up‐regulated in pancreatic carcinoma. The purpose… 
2005
2005
Ductal carcinoma in situ of the breast and heparanase-1 expression: a molecular explanation for more aggressive subtypes.
Highly Cited
2003
Highly Cited
2003
Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome
Ubiquitin (Ub) attachment to cell surface proteins causes their lysosomal degradation by incorporating them into lumenal… 
Highly Cited
2002
Highly Cited
2002
Heparanase-1 expression is associated with the metastatic potential of breast cancer.
BACKGROUND Metastasis of malignant breast cells is in part mediated through degradation of the extra-cellular matrix by… 
Highly Cited
2002
Highly Cited
2002
Human heparanase-1 gene expression in pancreatic adenocarcinoma
Highly Cited
1999
Highly Cited
1999
Cooperative Binding of Heat Shock Factor to the Yeast HSP82 Promoter In Vivo and In Vitro
ABSTRACT Previous work has shown that heat shock factor (HSF) plays a central role in remodeling the chromatin structure of the… 
Highly Cited
1998
Highly Cited
1998
Heat Shock Element Architecture Is an Important Determinant in the Temperature and Transactivation Domain Requirements for Heat Shock Transcription Factor
ABSTRACT The baker’s yeast Saccharomyces cerevisiae possesses a single gene encoding heat shock transcription factor (HSF), which… 
Highly Cited
1997
Highly Cited
1997
The yeast HRS1 gene is involved in positive and negative regulation of transcription and shows genetic characteristics similar to SIN4 and GAL11.
We provide genetic evidence that HRS1/PGD1, a yeast gene previously identified as a suppressor of the hyper-recombination… 
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