Skip to search formSkip to main contentSkip to account menu

HPRT1 gene

Known as: HYPOXANTHINE GUANINE PHOSPHORIBOSYLTRANSFERASE 1, Hypoxanthine Phosphoribosyltransferase 1 (Lesch-Nyhan Syndrome) Gene, HGPRT 
This gene is involved in purine/pyrimidine metabolism.
National Institutes of Health

Related topics

Related topics

7 relations
GoutHPRT1 wt AlleleHypoxanthine PhosphoribosyltransferaseLesch-Nyhan Syndrome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Lesch-Nyhan disease: I. Construction of expression vectors for hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme and amyloid precursor protein (APP)
Abstract Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorder of purine metabolism in which the enzyme… 
2017
2017
Reference gene selection for the shell gland of laying hens in response to time-points of eggshell formation and nicarbazin
Ten reference genes were investigated for normalization of gene expression data in the shell gland of laying hens. Analyses… 
2017
2017
The Mutagenic Potential of 3 , 5-Dimethylaminophenol in Bacterial and Mammalian Cells
Alkylanilines are ubiquitous environmental chemicals. Most individuals are subject to lifelong exposure to these compounds and… 
2014
2014
Lentiviral vectors encoding zinc-finger nucleases specific for the model target locus HPRT1.
Zinc-finger nucleases (ZFNs) are artificial proteins designed to induce double-stranded DNA breaks (DSBs) at predefined… 
2011
2011
Abstract 3213: Induction chemotherapy for stage 4 gastric cancer and prognostic molecular markers
The prognosis of gastric cancer with distant metastasis is very poor. Improvement of chemotherapy and investigation of molecular… 
2008
2008
Expression of X‐linked genes in deceased neonates and surviving cloned female piglets
Animal cloning through somatic cell nuclear transfer (NT) is very inefficient, probably due to insufficient reprogramming of the… 
1996
1996
Age dependent selection against HPRT deficient T lymphocytes in the HPRT+/- heterozygous mouse.
Highly Cited
1992
Highly Cited
1992
V(D)J recombinase-mediated deletion of the hprt gene in T-lymphocytes from adult humans.
1976
1976
Liver regeneration after experimental injury. Edited Rainer Lesch and Werner Reutter. 180 × 255 mm. Pp. 364 + x. Illustrated. 1975. New York: Stratton. $26.75
1975
1975
Reversion in expression of hypoxanthine-guanine phosphoribosyl transferase following cell hybridization.
Hybridization of mutant cell lines deficient in hypoxanthine-guanine phosphoribosyl transferase (HGPRT; E.C.: 2.4.2.8) from a… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)