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HPGD wt Allele

Known as: 15-PGDH, Hydroxyprostaglandin Dehydrogenase 15-(NAD) wt Allele, PHOAR1 
Human HPGD wild-type allele is located within 4q34-q35 and is approximately 32 kb in length. This allele, which encodes 15-hydroxyprostaglandin… 
National Institutes of Health

Related topics

Related topics

8 relations
15-Hydroxyprostaglandin Dehydrogenase [NAD+], human15-Hydroxyprostaglandin dehydrogenase (NAD+)4q34-q35Eicosanoid Modulation

Broader (1)

HPGD gene

Papers overview

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2018
2018
Biochemical characterization of protoporphyrinogen dehydrogenase and protoporphyrin ferrochelatase of Vibrio vulnificus and the critical complex formation between these enzymes.
2014
2014
Discovery of Novel Allosteric Effectors Based on the Predicted Allosteric Sites for Escherichia coli D-3-Phosphoglycerate Dehydrogenase
D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis, and can… 
2008
2008
15‐hydroxyprostaglandin dehydrogenase suppresses K‐RasV12‐dependent tumor formation in Nu/Nu mice
Oncogenic Ras mutations are early genetic events in colorectal cancer that induce cyclooxygenase (COX)‐2 expression and… 
2008
2008
Opposite Effect of Phorbol Ester PMA on PTGS2 and PGDH mRNA Expression in Human Chorion Trophoblast Cells
Prostaglandins (PGs) induce the mechanism of labor in humans. The enzymes responsible for PG synthesis and metabolism are… 
2008
2008
Effect of calcium ionophore A23187 on prostaglandin synthase type 2 and 15-hydroxy-prostaglandin dehydrogenase expression in human chorion trophoblast cells.
2004
2004
Quantitative Relationships of Site to Site Interaction in Escherichia coli d-3-Phosphoglycerate Dehydrogenase Revealed by Asymmetric Hybrid Tetramers*
A set of asymmetric hybrid tetramers of Escherichia coli d-3-phosphoglycerate dehydrogenase (PGDH) have been made by gene co… 
2002
2002
Cortisol/progesterone antagonism in regulation of 15-hydroxysteroid dehydrogenase activity and mRNA levels in human chorion and placental trophoblast cells at term.
PGs mediate parturition events. 15-Hydroxyprostaglandin dehydrogenase (PGDH) catalyzes the first step in the metabolism of PGs to… 
1989
1989
Evidence for several fold more activity of NAD+-dependent uterine prostaglandin 15-hydroxydehydrogenase in transsexual than in non-transsexual women.
1988
1988
Human placental 15-hydroxy-prostaglandin dehydrogenase activity is under fetal genetic control.
1983
1983
Novel prostaglandin dehydrogenase in rat skin.
Present evidence suggests that skin is an important organ of prostaglandin metabolism. To clarify its role, the basic kinetics of… 
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