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HPGD wt Allele
Known as:
15-PGDH
, Hydroxyprostaglandin Dehydrogenase 15-(NAD) wt Allele
, PHOAR1
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Human HPGD wild-type allele is located within 4q34-q35 and is approximately 32 kb in length. This allele, which encodes 15-hydroxyprostaglandin…
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National Institutes of Health
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Related topics
Related topics
8 relations
15-Hydroxyprostaglandin Dehydrogenase [NAD+], human
15-Hydroxyprostaglandin dehydrogenase (NAD+)
4q34-q35
Eicosanoid Modulation
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Broader (1)
HPGD gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Loss of 15-hydroxyprostaglandin dehydrogenase expression contributes to bladder cancer progression.
Stephanie S. Tseng-Rogenski
,
J. Gee
,
+10 authors
M. Liebert
American Journal of Pathology
2010
Corpus ID: 7141767
Prostaglandin E2, which is known to contribute to cancer progression, is inactivated by the catabolic enzyme, 15…
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Highly Cited
2008
Highly Cited
2008
Expression of 15-PGDH is downregulated by COX-2 in gastric cancer.
Zhenxiong Liu
,
Xin Wang
,
+8 authors
D. Fan
Carcinogenesis
2008
Corpus ID: 10014086
To explore the proteins regulated by cyclooxygenase-2 (COX-2) in gastric cancer, the expression plasmid of COX-2siRNA was…
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2005
2005
D-3-Phosphoglycerate Dehydrogenase from Mycobacterium tuberculosis Is a Link between the Escherichia coli and Mammalian Enzymes*
S. Dey
,
Zhiqin Hu
,
Xiao Lan Xu
,
J. Sacchettini
,
G. A. Grant
Journal of Biological Chemistry
2005
Corpus ID: 21538093
d-3-Phosphoglycerate dehydrogenase (PGDH) from Mycobacterium tuberculosis has been isolated to homogeneity and displays an…
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Highly Cited
2003
Highly Cited
2003
Bacterially-Induced Preterm Labor and Regulation of Prostaglandin-Metabolizing Enzyme Expression in Mice: The Role of Toll-Like Receptor 41
Hao Wang
,
E. Hirsch
Biology of Reproduction
2003
Corpus ID: 25823891
Abstract Toll-like receptor 4 (TLR-4) is a critical mediator of the cellular response to lipopolysaccharide. Our purpose was to…
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2003
2003
Genomic structure and transcriptional regulation of the human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene.
A. Nandy
,
S. Jenatschke
,
B. Hartung
,
K. Milde‐Langosch
,
A. Bamberger
,
B. Gellersen
Journal of Molecular Endocrinology
2003
Corpus ID: 19097290
The NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (PGDH) is a catabolic enzyme that controls the biological activities…
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Review
2001
Review
2001
Understanding Preterm Labor
J. Challis
,
S. Lye
,
W. Gibb
,
W. Whittle
,
F. Patel
,
N. Alfaidy
Annals of the New York Academy of Sciences
2001
Corpus ID: 27866661
Increased uterine contractility at term and preterm results from activation and then stimulation of the myometrium. Activation…
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Highly Cited
2000
Highly Cited
2000
The human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene promoter is controlled by Ets and activating protein-1 transcription factors and progesterone.
K. Greenland
,
I. Jantke
,
S. Jenatschke
,
K. Bracken
,
C. Vinson
,
B. Gellersen
Endocrinology
2000
Corpus ID: 25047514
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (PGDH) is a key catabolic enzyme in the inactivation of PGF2alpha and PGE2…
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Highly Cited
1999
Highly Cited
1999
Steroid regulation of prostaglandin dehydrogenase activity and expression in human term placenta and chorio-decidua in relation to labor.
F. Patel
,
V. Clifton
,
K. Chwalisz
,
J. Challis
Journal of Clinical Endocrinology and Metabolism
1999
Corpus ID: 20546027
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (PGDH) is the key catabolic enzyme controlling levels of biologically active…
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Review
1999
Review
1999
Prostaglandin dehydrogenase and the initiation of labor
J. Challis
,
F. Patel
,
F. Pomini
Journal of Perinatal Medicine
1999
Corpus ID: 41735394
Abstract In summary, these studies have suggested that prostaglandin dehydrogenase may have a central role to play in the…
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Highly Cited
1997
Highly Cited
1997
Chorionic prostaglandin catabolism is decreased in the lower uterine segment with term labour.
C. V. van Meir
,
M. Ramirez
,
S. Matthews
,
A. Calder
,
M. Keirse
,
J. Challis
Placenta
1997
Corpus ID: 4547083
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