HPGD gene

Known as: Hydroxyprostaglandin Dehydrogenase 15-(NAD) Gene, short chain dehydrogenase/reductase family 36C, member 1, 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE, TYPE I 
This gene is involved in prostaglandin metabolism.
National Institutes of Health

Related topics

Related topics

7 relations
15-Hydroxyprostaglandin Dehydrogenase [NAD+], human15-Hydroxyprostaglandin dehydrogenase (NAD+)Eicosanoid ModulationHPGDS gene
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HPGD wt Allele

Papers overview

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2014
2014
Aspirin and the Risk of Colorectal Cancer in Relation to the Expression of 15-Hydroxyprostaglandin Dehydrogenase (HPGD)
Aspirin use reduces the risk of colorectal neoplasia, at least in part, through inhibition of prostaglandin-endoperoxide synthase… (More)
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2014
2014
miR-485-5p Binding Site SNP rs8752 in HPGD Gene Is Associated with Breast Cancer Risk
BACKGROUND Single nucleotide polymorphisms (SNPs) that reside in microRNA target sites may play an important role in breast… (More)
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2013
2013
Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis.
In plants, two independent serine biosynthetic pathways, the photorespiratory and glycolytic phosphoserine (PS) pathways, have… (More)
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2011
2011
Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.
The arachidonic acid and prostaglandin pathway has been implicated in prostate carcinogenesis, but comprehensive studies of the… (More)
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2009
2009
Homozygous mutations in the 15-hydroxyprostaglandin dehydrogenase gene in patients with primary hypertrophic osteoarthropathy
Mutations in HPGD have recently been reported to cause primary hypertrophic osteoarthropathy (PHO), a rare genetic disease… (More)
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2008
2008
Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells.
The expression of hTERT, the catalytic subunit of telomerase, immortalizes normal human urothelial cells (NHUC). Expression of a… (More)
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2008
2008
Mutation in the HPGD gene encoding NAD+ dependent 15-hydroxyprostaglandin dehydrogenase underlies isolated congenital nail clubbing (ICNC).
BACKGROUND Isolated congenital nail clubbing (ICNC) is a rare autosomal recessive disorder characterised by enlargement of the… (More)
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2007
2007
Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer.
Evidence indicates that the induction of cyclooxygenase-2 (COX-2) and high prostaglandin E2 (PGE2) levels contribute to the… (More)
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Highly Cited
2007
Highly Cited
2007
Transcriptomic dissection of tongue squamous cell carcinoma
The head and neck/oral squamous cell carcinoma (HNOSCC) is a diverse group of cancers, which develop from many different anatomic… (More)
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2006
2006
Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells.
Human lung adenocarcinoma cells, A549, possess the capacity of expressing both cyclooxygenase-2 (COX-2) and NAD+-linked 15… (More)
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