HOXD13 gene

Known as: Homeobox D13 Gene, HOMEOBOX D13, HOX4I 
This gene plays a role in the development of limbs and appendages.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
0519962017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
OBJECTIVES To present the association of hypospadias with hypoplastic synpolydactyly and discuss the molecular genetic basis of… (More)
Is this relevant?
2007
2007
HOXD13, the homeobox-containing gene located at the most 5' end of the HOXD cluster, plays a critical role in limb development… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
HOX genes, notably members of the HOXA cluster, and HOX cofactors have increasingly been linked to human leukemia. Intriguingly… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
2002
2002
Studies in mouse and chick have shown that the 5' HoxD genes play major roles in the development of the limbs and genitalia. In… (More)
Is this relevant?
2001
2001
Polyalanine expansion in the human HOXD13 gene induces synpolydactyly (SPD), an inherited congenital limb malformation. A mouse… (More)
Is this relevant?
2000
2000
We report the characterization of a rare chromosomal translocation, a t(2;11)(q31;p15), which occurred in a patient with de novo… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1998
1998
Human synpolydactyly (SPD) is an inherited congenital limb malformation caused by mutations in the HOXD13 gene. Heterozygotes are… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation. Typical cases have 3/4 finger and 4/5 toe syndactyly… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Hox genes regulate patterning during limb development. It is believed that they function in the determination of the timing and… (More)
Is this relevant?
1996
1996
Synpolydactyly (SPD) is a limb malformation that shows a characteristic manifestation in both hands and feet. This condition is… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?