FAQ

Homeobox Protein Hox-D13

Known as: HOXD13, Homeobox Protein Hox-4I 
Homeobox protein Hox-D13 (343 aa, ~36 kDa) is encoded by the human HOXD13 gene. This protein plays a role in transcriptional modulation that mediates… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
051019952017

Related topics

Related topics

9 relations
Cell NucleusDNA-Binding ProteinsGenes, RegulatorHOXD13 gene
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Homeobox Protein Hox-D13
Cell Nucleus
dna binding
Genes, Regulator
Transcriptional Regulation
DNA-Binding Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A.
The morphology of bones is genetically determined, but the molecular mechanisms that control shape, size and the overall gestalt… (More)
Is this relevant?
2007
2007
Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.
The t(2;11)(q31;p15) chromosomal translocation results in a fusion between the NUP98 and HOXD13 genes and has been observed in… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas.
Aberrant methylation of promoter CpG islands (CGI) is involved in silencing of tumor suppressor genes and is also a potential… (More)
  • table 1
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
2005
2005
Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.
AbdB-like HOX proteins form DNA-binding complexes with the TALE superclass proteins MEIS1A and MEIS1B, and trimeric complexes… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1.
HOX genes, notably members of the HOXA cluster, and HOX cofactors have increasingly been linked to human leukemia. Intriguingly… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
1999
1999
NUP98 is fused to PMX1 homeobox gene in human acute myelogenous leukemia with chromosome translocation t(1;11)(q23;p15).
The nucleoporin gene NUP98 was found fused to the HOXA9, HOXD13, or DDX10 genes in human acute myelogenous leukemia (AML) with… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia.
A novel chromosomal translocation, t(2;11)(q31;p15), was identified in a patient with therapy-related acute myelogenous leukemia… (More)
  • figure I
  • figure 2
  • table 1
  • figure 3
Is this relevant?
1998
1998
Deletions in HOXD13 segregate with an identical, novel foot malformation in two unrelated families.
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation consisting of 3/4 syndactyly in the hands and 4/5… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Synpolydactyly phenotypes correlate with size of expansions in HOXD13 polyalanine tract.
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation. Typical cases have 3/4 finger and 4/5 toe syndactyly… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13.
Hox genes regulate patterning during limb development. It is believed that they function in the determination of the timing and… (More)
Is this relevant?