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Homeobox Protein Hox-D13
Known as:
HOXD13
, Homeobox Protein Hox-4I
Â
Homeobox protein Hox-D13 (343 aa, ~36 kDa) is encoded by the human HOXD13 gene. This protein plays a role in transcriptional modulation that mediates…Â
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1995-2017
0
5
10
1995
2017
Related topics
Related topics
9 relations
Cell Nucleus
DNA-Binding Proteins
Genes, Regulator
HOXD13 gene
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Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Homeobox Protein Hox-D13
Cell Nucleus
dna binding
Genes, Regulator
Transcriptional Regulation
DNA-Binding Proteins
Papers overview
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2014
2014
Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A.
Pia Kuss
,
Katerina Kraft
,
+4 authors
Sigmar Stricker
Developmental biology
2014
The morphology of bones is genetically determined, but the molecular mechanisms that control shape, size and the overall gestalt…Â
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2007
2007
Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation.
Christopher I. Slape
,
Helge Hartung
,
Ying-wei Lin
,
Juraj Bies
,
Linda Wolff
,
Peter D Aplan
Cancer research
2007
The t(2;11)(q31;p15) chromosomal translocation results in a fusion between the NUP98 and HOXD13 genes and has been observed in…Â
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Highly Cited
2006
Highly Cited
2006
Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas.
Junichi Furuta
,
Yoshimasa Nobeyama
,
Yoshihiro Umebayashi
,
Fujio Otsuka
,
Kanako Kikuchi
,
Toshikazu Ushijima
Cancer research
2006
Aberrant methylation of promoter CpG islands (CGI) is involved in silencing of tumor suppressor genes and is also a potential…Â
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2005
2005
Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.
Thomas Michael Williams
,
Melissa E. Williams
,
Jeffrey W. Innis
Developmental biology
2005
AbdB-like HOX proteins form DNA-binding complexes with the TALE superclass proteins MEIS1A and MEIS1B, and trimeric complexes…Â
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Highly Cited
2003
Highly Cited
2003
Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1.
Nicolas Pineault
,
Christian Buske
,
+5 authors
R. Keith Humphries
Blood
2003
HOX genes, notably members of the HOXA cluster, and HOX cofactors have increasingly been linked to human leukemia. Intriguingly…Â
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1999
1999
NUP98 is fused to PMX1 homeobox gene in human acute myelogenous leukemia with chromosome translocation t(1;11)(q23;p15).
T. Nakamura
,
Y. Yamazaki
,
Y. Hatano
,
Iwao Miura
Blood
1999
The nucleoporin gene NUP98 was found fused to the HOXA9, HOXD13, or DDX10 genes in human acute myelogenous leukemia (AML) with…Â
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Highly Cited
1998
Highly Cited
1998
NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia.
Samina Z. Raza-Egilmez
,
Sheila N. Jani-Sait
,
Mauro Grossi
,
M. J. Higgins
,
T. B. Shows
,
Peter D Aplan
Cancer research
1998
A novel chromosomal translocation, t(2;11)(q31;p15), was identified in a patient with therapy-related acute myelogenous leukemia…Â
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1998
1998
Deletions in HOXD13 segregate with an identical, novel foot malformation in two unrelated families.
Frances R. Goodman
,
Maria Luisa Giovannucci-Uzielli
,
C. P. Hall
,
Willie Reardon
,
R. Winter
,
Peter J. Scambler
American journal of human genetics
1998
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation consisting of 3/4 syndactyly in the hands and 4/5…Â
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Highly Cited
1997
Highly Cited
1997
Synpolydactyly phenotypes correlate with size of expansions in HOXD13 polyalanine tract.
F. R. Goodman
,
Stefan Mundlos
,
+11 authors
Peter J. Scambler
Proceedings of the National Academy of Sciences…
1997
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation. Typical cases have 3/4 finger and 4/5 toe syndactyly…Â
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Highly Cited
1996
Highly Cited
1996
Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13.
Yoshinori Muragaki
,
Stefan Mundlos
,
J. Upton
,
Brady Olsen
Science
1996
Hox genes regulate patterning during limb development. It is believed that they function in the determination of the timing and…Â
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