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Homeobox Protein Hox-D13

Known as: HOXD13, Homeobox Protein Hox-4I 
Homeobox protein Hox-D13 (343 aa, ~36 kDa) is encoded by the human HOXD13 gene. This protein plays a role in transcriptional modulation that mediates… Expand
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
VACTERL acronym is assigned to a non-random association of malformations in humans with poorly known etiology. It is comprised of… Expand
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Highly Cited
2007
Highly Cited
2007
HOXD13, the homeobox-containing gene located at the most 5' end of the HOXD cluster, plays a critical role in limb development… Expand
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Highly Cited
2006
Highly Cited
2006
Aberrant methylation of promoter CpG islands (CGI) is involved in silencing of tumor suppressor genes and is also a potential… Expand
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Highly Cited
2006
Highly Cited
2006
Several types of tumors are known to originate from the pineal region, among them pineal parenchymal tumors (PPTs) and papillary… Expand
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2006
2006
Hoxa and Hoxd genes, related to the Drosophila Abd-B gene, display regionally restricted expression patterns and are necessary… Expand
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Highly Cited
2005
Highly Cited
2005
AbdB-like HOX proteins form DNA-binding complexes with the TALE superclass proteins MEIS1A and MEIS1B, and trimeric complexes… Expand
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2005
2005
Hox genes encode transcription factors that regulate the morphogenesis of developing embryos. In mammals, knowledge of the… Expand
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1998
1998
Human synpolydactyly (SPD) is an inherited congenital limb malformation caused by mutations in the HOXD13 gene. Heterozygotes are… Expand
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1998
1998
Synpolydactyly (SPD) is a dominantly inherited congenital limb malformation consisting of 3/4 syndactyly in the hands and 4/5… Expand
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Highly Cited
1996
Highly Cited
1996
Hox genes regulate patterning during limb development. It is believed that they function in the determination of the timing and… Expand
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