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The Evolution of the DLK1-DIO3 Imprinted Domain in Mammals
TLDR
The imprinting status, DNA methylation, and genomic landscape of the Dlk1-Dio3 cluster were determined in eutherian, metatherian, and prototherian mammals including tammar wallaby and platypus. Expand
Maternal Regulation of Milk Composition, Milk Production, and Pouch Young Development During Lactation in the Tammar Wallaby (Macropus eugenii )1
TLDR
It is demonstrated that the lactating tammar wallaby regulates both milk composition and the rate of milk production and that these determine the rates of PY growth and development, irrespective of the age of the PY. Expand
Retrotransposon Silencing by DNA Methylation Can Drive Mammalian Genomic Imprinting
TLDR
It is provided the first demonstration that DMR-associated genomic imprinting in eutherians can originate from the repression of exogenous DNA sequences and/or retrotransposons by DNA methylation. Expand
Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians
TLDR
The conservation in all therians of the mechanism controlling imprinting of the IGF2-H19 locus suggests a sequential model of imprinting evolution. Expand
Evolution of vertebrate interferon inducible transmembrane proteins
TLDR
This study characterised IFITMs in two distantly related marsupial species, the Australian tammar wallaby and the South American grey short-tailed opossum, and analysed the phylogeny of the IFITM family in vertebrates. Expand
Eggs, embryos and the evolution of imprinting: insights from the platypus genome.
TLDR
Comparing the distribution of repeat elements known to attract epigenetic silencing across the genome from monotremes and therian mammals, particularly focusing on the orthologous imprinted regions shows that the platypus has significantly fewer repeats of certain classes in the regions of the genome that have become imprinted in therians. Expand
Evolution of genomic imprinting: insights from marsupials and monotremes.
TLDR
It is shown that imprinting was not essential for the evolution of the placenta and its importance in nutrient transfer but the elaboration of imprinted genes in marsupials and eutherians is associated with viviparity. Expand
DDX4 (VASA) Is Conserved in Germ Cell Development in Marsupials and Monotremes1
TLDR
Data suggest that DDX4 is essential for the regulation of germ cell proliferation and differentiation across all three extant mammalian groups—eutherians, marsupials, and monotremes. Expand
Evolution of the CDKN1C-KCNQ1 imprinted domain
TLDR
Findings demonstrate the stepwise accumulation of control mechanisms within imprinted domains and show that CDKN1C imprinting cannot be due to its synteny with IGF2 or with its placental expression in mammals. Expand
Experimental manipulation of sexual differentiation in wallaby pouch young treated with exogenous steroids.
TLDR
These experiments show that marsupials, like eutherians, have a dual hormonal control of Wolffian and Müllerian development and the initial development of the mammary glands, pouch, gubernaculum and scrotum does not appear to be under hormonal control and is therefore likely to be autonomous and dependent on genotype. Expand
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