HOTAIR gene

Known as: HOXC11-AS1, HOXC-AS4, HOXC cluster antisense RNA 4 (non-protein coding) 
This gene plays a role in the repression of HOXD gene expression.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and… (More)
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Highly Cited
2013
Highly Cited
2013
Accumulating evidence indicates that the long non-coding RNA HOTAIR plays a critical role in cancer progression and metastasis… (More)
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Highly Cited
2012
Highly Cited
2012
Large intergenic noncoding RNAs (lincRNA) have been less studied than miRNAs in cancer, although both offer considerable… (More)
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Highly Cited
2011
Highly Cited
2011
The functional impact of recently discovered long noncoding RNAs (ncRNAs) in human cancer remains to be clarified. One long ncRNA… (More)
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Highly Cited
2011
Highly Cited
2011
The long noncoding RNA HOTAIR has been reported as a poor prognostic biomarker in patients with breast cancer. The aim of the… (More)
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Highly Cited
2011
Highly Cited
2011
Increasing evidence suggests that large intervening non-coding RNAs (lincRNAs) regulate key pathways in cancer invasion and… (More)
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Highly Cited
2010
Highly Cited
2010
Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome yet their potential involvement in human… (More)
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Highly Cited
2010
Highly Cited
2010
Long intergenic noncoding RNAs (lincRNAs) regulate chromatin states and epigenetic inheritance. Here, we show that the lincRNA… (More)
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Highly Cited
2009
Highly Cited
2009
We recently showed that the mammalian genome encodes >1,000 large intergenic noncoding (linc)RNAs that are clearly conserved… (More)
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Highly Cited
2007
Highly Cited
2007
Noncoding RNAs (ncRNA) participate in epigenetic regulation but are poorly understood. Here we characterize the transcriptional… (More)
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