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HOTAIR gene

Known as: HOXC11-AS1, HOXC-AS4, HOXC cluster antisense RNA 4 (non-protein coding) 
This gene plays a role in the repression of HOXD gene expression.
National Institutes of Health

Related topics

Related topics

3 relations
HOTAIR long untranslated RNA, humanTranscriptional RegulationTranscriptional Repression

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Retracted: Long noncoding RNA HOTAIR knockdown inhibits autophagy and epithelial–mesenchymal transition through the Wnt signaling pathway in radioresistant human cervical cancer HeLa cells
Cervical cancer is one of the most common female malignancies around the world, and radiation resistance is a major obstacle to… 
2017
2017
Propofol promotes apoptosis and suppresses the HOTAIR-mediated mTOR/p70S6K signaling pathway in melanoma cells.
Propofol is an intravenous anesthetic, which is widely used in clinical anesthesia induction and maintenance and is critical in… 
2017
2017
LncRNA HOTAIR contributes to the tumorigenesis of nasopharyngeal carcinoma via up-regulating FASN.
Objective The therapeutic options for nasopharyngeal carcinoma (NPC) treatment have been restricted mainly to radiotherapy or… 
Highly Cited
2016
Highly Cited
2016
A Feed-Forward Regulatory Loop between HuR and the Long Noncoding RNA HOTAIR Promotes Head and Neck Squamous Cell Carcinoma Progression and Metastasis
Background/Aims: The lncRNA Homeobox (HOX) transcript antisense RNA (HOTAIR) is overexpressed in numerous cancers. HuR is also… 
Highly Cited
2016
Highly Cited
2016
A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer
Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer-related death worldwide, and the 5-year survival rate… 
2016
2016
Specific long non-coding RNAs response to occupational PAHs exposure in coke oven workers
2016
2016
Comment on "Hotair Is Dispensable for Mouse Development"
Amandio et al. [1] reanalyzed a Hotair knockout (KO) mouse allele previously reported by Li et al. [2]. The authors evaluated the… 
Highly Cited
2015
Highly Cited
2015
Erratum to: Overexpression of long non-coding RNA HOTAIR leads to chemoresistance by activating the Wnt/β-catenin pathway in human ovarian cancer
Overexpression of HOTAIR (HOX antisense intergenic RNA) is significantly correlated with tumor progression and poor prognosis in… 
Highly Cited
2015
Highly Cited
2015
HOTAIR Interacting with MAPK1 Regulates Ovarian Cancer skov3 Cell Proliferation, Migration, and Invasion
Background The aim of this study was to evaluate the effect of when silencing HOTAIR in ovarian cancer skov3 cells on… 
2012
2012
Upregulation of miR-196 a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors
Large intergenic noncoding RNAs (lincRNA) have been less studied thanmiRNAs in cancer, although both offer considerable… 
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