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HK2 gene

Known as: HEXOKINASE 2, HK2, Hexokinase 2 Gene 
This gene plays a role in carbohydrate metabolism and cell cycle progression.
National Institutes of Health

Related topics

Related topics

5 relations
GlycolysisHK2 wt AlleleHOOK1 geneHexokinase 2

Papers overview

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Highly Cited
2015
Highly Cited
2015
The combination of the expression of hexokinase 2 and pyruvate kinase M2 is a prognostic marker in patients with pancreatic cancer.
Metabolism may determine the biologically malignant behavior of pancreatic cancer. To investigate the significance and prognostic… 
2014
2014
Expression of hexokinase 2 in epithelial ovarian tumors and its clinical significance in serous ovarian cancer.
"Warburg effect" emphasizes that malignant cells exhibit active glycolysis even under aerobic conditions. Hexokinase 2 (HK2) is a… 
1999
1999
New ultrasensitive assays facilitate studies on the role of human glandular kallikrein (hK2) as a marker for prostatic disease.
Prostate cancer is the most common non-skin cancer in men, and it is an important cause of morbidity and mortality. The growth… 
Highly Cited
1998
Highly Cited
1998
Human glandular kallikrein, hK2, shows arginine‐restricted specificity and forms complexes with plasma protease inhibitors
Human glandular kallikrein (hK2) is a new potential marker for prostate cancer. It is a serine protease expressed in human… 
Highly Cited
1998
Highly Cited
1998
Detection of human glandular kallikrein, hK2, as its precursor form and in complex with protease inhibitors in prostate carcinoma serum.
Forms of human glandular kallikrein (kK2) in prostate carcinoma serum were identified using monoclonal antibodies specific for… 
Highly Cited
1998
Highly Cited
1998
Development of monoclonal antibodies specific for human glandular kallikrein (hK2): development of a dual antibody immunoassay for hK2 with negligible prostate-specific antigen cross-reactivity.
Highly Cited
1997
Highly Cited
1997
Serpin-derived Peptide Substrates for Investigating the Substrate Specificity of Human Tissue Kallikreins hK1 and hK2*
The third human tissue kallikrein to be identified, hK2, could be an alternate or complementary marker to kallikrein hK3… 
Highly Cited
1997
Highly Cited
1997
Detection of a prostate-specific protein, human glandular kallikrein (hK2), in sera of patients with elevated prostate-specific antigen levels.
Highly Cited
1996
Highly Cited
1996
Expression of human glandular kallikrein, hK2, in mammalian cells.
The human kallikrein family consists of three members, hK1, hK2, and hK3 [prostate-specific antigen (PSA)]. PSA is a widely… 
1995
1995
Overexpression of a human prostate-specific glandular kallikrein, hK2, in E. coli and generation of antibodies
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