HIV Protease

Known as: p16 protease, HIV, HTLV-III Protease, HIV Protease [Chemical/Ingredient] 
Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional… (More)

Topic mentions per year

Topic mentions per year

1987-2017
0204019872017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Human immunodeficiency virus (HIV) has a small genome and therefore relies heavily on the host cellular machinery to replicate… (More)
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Highly Cited
2009
Highly Cited
2009
We describe the testing and release of AutoDock4 and the accompanying graphical user interface AutoDockTools. AutoDock4… (More)
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Highly Cited
2008
Highly Cited
2008
We introduce human proteome–derived, database-searchable peptide libraries for characterizing sequence-specific protein… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE The development of new cancer drugs is slow and costly. HIV protease inhibitors are Food and Drug Administration approved… (More)
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2006
2006
The PABP [poly(A)-binding protein] is able to interact with the 3' poly(A) tail of eukaryotic mRNA, promoting its translation… (More)
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Highly Cited
2001
Highly Cited
2001
Highly active anti-retroviral therapies, which incorporate HIV protease inhibitors, resolve many AIDS-defining illnesses. However… (More)
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Highly Cited
1999
Highly Cited
1999
At present, treatment of HIV infection uses small inhibitory molecules that target HIV protease; however, the emergence of… (More)
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Highly Cited
1996
Highly Cited
1996
Analysis of the HIV protease gene from the plasma of HIV–infected patients revealed substitutions at nine different codons… (More)
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1995
1995
HIV protease is a homodimeric protein whose activity is essential to viral function. We have investigated the molecular dynamics… (More)
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Highly Cited
1988
Highly Cited
1988
Retroviral proteins are synthesized as polyprotein precursors that undergo proteolytic cleavages to yield the mature viral… (More)
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