Skip to search formSkip to main contentSkip to account menu

p16 protease, Human immunodeficiency virus 1

Known as: p16 protease, HIV-1, p16 pol gene product, HIV-1, p16 pol gene product, Human immunodeficiency virus 1 
National Institutes of Health

Related topics

Related topics

2 relations
Aspartic Acid Endopeptidases

Broader (1)

HIV Protease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Elucidating a relationship between conformational sampling and drug resistance in HIV-1 protease.
Enzyme targets in rapidly replicating systems, such as retroviruses, commonly respond to drug-selective pressure with mutations… 
2009
2009
Monitoring inhibitor-induced conformational population shifts in HIV-1 protease by pulsed EPR spectroscopy.
Double electron-electron resonance (DEER), a pulsed electron paramagnetic resonance (EPR) spectroscopy technique, was utilized to… 
2007
2007
Protein-protein Interactions as New Targets for Drug Design: Virtual and Experimental Approaches
Protein-protein and protein-ligand interactions play a central role in biochemical reactions, and understanding these processes… 
2007
2007
Disruption of the HIV-1 protease dimer with interface peptides: structural studies using NMR spectroscopy combined with [2-(13)C]-Trp selective labeling.
HIV-1 protease (HIV-1 PR), which is encoded by retroviruses, is required for the processing of gag and pol polyprotein precursors… 
Review
2003
Review
2003
HIV-1 protease inhibitors: a comparative QSAR analysis.
An excellent example in the field of rational drug design is the discovery and development of more than a dozen drugs for the… 
2003
2003
HIV-1 proprotein processing as a target for gene therapy
The central role of endoconvertases and HIV-1 protease (HIV-1 PR) in the processing of HIV proproteins makes the design of… 
2003
2003
HIV-1 protease inhibitory effects of some selected plants in Caesalpiniaceae and Papilionaceae families
Tewtrakul, S., Subhadhirasakul, S., and Rattanasuwan, P HIV-1 protease inhibitory effects of some selected plants in… 
2002
2002
Elucidating the inhibiting mode of AHPBA derivatives against HIV-1 protease and building predictive 3D-QSAR models.
The Lamarckian genetic algorithm of AutoDock 3.0 has been used to dock 27 3(S)-amino-2(S)-hydroxyl-4-phenylbutanoic acids (AHPBAs… 
1998
1998
Cyclic HIV protease inhibitors: design and synthesis of orally bioavailable, pyrazole P2/P2' cyclic ureas with improved potency.
Highly potent HIV-1 protease (HIVPR) inhibitors have been designed and synthesized by introducing bidentate hydrogen-bonding… 
1995
1995
Nonpeptidic potent HIV-1 protease inhibitors: (4-hydroxy-6-phenyl-2-oxo-2H- pyran-3-yl)thiomethanes that span P1-P2' subsites in a unique mode of active site binding.
Using molecular modeling and the information derived from the X-ray crystal structure of HIV-1 protease (HIV PR) complexed with… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)