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HES3 gene

Known as: HES3, bHLHb43, hes family bHLH transcription factor 3 
This gene plays a role in transcriptional repression.
National Institutes of Health

Related topics

Related topics

7 relations
Homo sapiensNeurogenesisTranscription Factor HES-3Transcriptional Regulation
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis
Alveolar rhabdomyosarcoma is a pediatric soft-tissue sarcoma caused by PAX3/7-FOXO1 fusion oncogenes and is characterized by… Expand
Review
2014
Review
2014
Expression dynamics and functions of Hes factors in development and diseases.
Hes genes, encoding basic helix-loop-helix (HLH) transcriptional repressors, are mammalian homologues of Drosophila hairy and… Expand
2013
2013
Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics
Tumors exhibit complex organization and contain a variety of cell populations. The realization that the regenerative properties… Expand
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Highly Cited
2012
Highly Cited
2012
The role of Hes genes in intestinal development, homeostasis and tumor formation
Notch signaling regulates intestinal development, homeostasis and tumorigenesis, but its precise downstream mechanism remains… Expand
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2011
2011
Polymorphisms of MAMLD1 gene in hypospadias.
PURPOSE Mastermind-like domain containing 1 (MAMLD1) is a causative gene for the fetal development of male external genitalia… Expand
Highly Cited
2007
Highly Cited
2007
Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal…
Notch signaling pathway maintains stem cells through transcriptional activation of HES/HEY family members to repress tissue… Expand
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Highly Cited
2004
Highly Cited
2004
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation
Radial glial cells derive from neuroepithelial cells, and both cell types are identified as neural stem cells. Neural stem cells… Expand
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2004
2004
Identification and characterization of human HES2, HES3, and HES5 genes in silico.
MMTV induces the mouse mammary tumor through the dysregulation of Notch, Wnt, or Fgf signaling pathway. Activation of Notch… Expand
Highly Cited
2001
Highly Cited
2001
Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain
The isthmic organizer, which is located at the midbrain–hindbrain boundary, plays an essential role in development of the… Expand
1997
1997
Expression of the helix-loop-helix factor, Hes3, during embryo development suggests a role in early midbrain-hindbrain patterning
  • C. Lobe
  • Mechanisms of Development
  • 1997
    • Corpus ID: 18405562
The Hes gene family members are mammalian homologues of the Drosophila hairy and Enhancer of split genes. hairy and Enhancer of… Expand
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