FAQ

HES3 gene

Known as: HES3, bHLHb43, hes family bHLH transcription factor 3 
This gene plays a role in transcriptional repression.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
02419972016

Related topics

Related topics

7 relations
Homo sapiensNeurogenesisTranscription Factor HES-3Transcriptional Regulation
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Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
HES3 gene
Transcriptional Regulation
dna binding
Neurogenesis
Homo sapiens
Transcriptional Repression

Papers overview

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2012
2012
Primitive cardiac cells from human embryonic stem cells.
Pluripotent stem cell-derived cardiomyocytes are currently being investigated for in vitro human heart models and as potential… (More)
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2012
2012
The role of Hes genes in intestinal development, homeostasis and tumor formation.
Notch signaling regulates intestinal development, homeostasis and tumorigenesis, but its precise downstream mechanism remains… (More)
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2010
2010
Up-scaling single cell-inoculated suspension culture of human embryonic stem cells.
We have systematically developed single cell-inoculated suspension cultures of human embryonic stem cells (hESC) in defined media… (More)
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Highly Cited
2007
Highly Cited
2007
Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal…
Notch signaling pathway maintains stem cells through transcriptional activation of HES/HEY family members to repress tissue… (More)
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2006
2006
Derivation of three clones from human embryonic stem cell lines by FACS sorting and their characterization.
Here we describe the first report of three human embryonic stem cell (hESC) clones, hES 3.1, 3.2, and 3.3, derived from the… (More)
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Highly Cited
2004
Highly Cited
2004
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation.
Radial glial cells derive from neuroepithelial cells, and both cell types are identified as neural stem cells. Neural stem cells… (More)
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Highly Cited
2002
Highly Cited
2002
Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain
Notch signaling plays a pivotal role in the regulation of vertebrate neurogenesis. However, in vitro experiments suggest that… (More)
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Highly Cited
2001
Highly Cited
2001
Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.
The isthmic organizer, which is located at the midbrain-hindbrain boundary, plays an essential role in development of the… (More)
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2000
2000
Generation of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons.
The basic helix-loop-helix gene Hes3 is expressed by differentiating and mature Purkinje cells in the cerebellum and by neural… (More)
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1997
1997
Expression of the helix-loop-helix factor, Hes3, during embryo development suggests a role in early midbrain-hindbrain patterning
The Hes gene family members are mammalian homologues of the Drosophila hairy and Enhancer of split genes. hairy and Enhancer of… (More)
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