FAQ

HES2 protein, human

Known as: bHLHb40, HES-2, hairy and enhancer of split 2 (Drosophila) protein, human 
Transcription factor HES-2 (173 aa, ~18 kDa) is encoded by the human HES2 gene. This protein is involved in the repression of transcription.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2014
01219932014

Related topics

Related topics

13 relations
Basic Helix-Loop-Helix Transcription FactorsCell NucleusDNA-Binding ProteinsGenes, Regulator
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Broader (1)

TRANSCRIPTION FACTOR

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
HES2 protein, human
Cell Nucleus
TRANSCRIPTION FACTOR
dna binding
Genes, Regulator
protein protein interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells.
Self-renewable human pluripotent stem cells (hPSCs) serve as a potential unlimited ex vivo source of human cardiomyocytes (CMs… (More)
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2012
2012
Human Pluripotent Stem Cell-Derived Cardiomyocytes: Response to TTX and Lidocain Reveals Strong Cell to Cell Variability
Stem cell derived cardiomyocytes generated either from human embryonic stem cells (hESC-CMs) or human induced pluripotent stem… (More)
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2008
2008
Distinct cardiogenic preferences of two human embryonic stem cell (hESC) lines are imprinted in their proteomes in the pluripotent state.
Although both the H1 and HES2 human embryonic stem cell lines (NIH codes: WA01 and ES02, respectively) are capable of forming all… (More)
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Highly Cited
2007
Highly Cited
2007
Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal…
Notch signaling pathway maintains stem cells through transcriptional activation of HES/HEY family members to repress tissue… (More)
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Highly Cited
2007
Highly Cited
2007
Functional sarcoplasmic reticulum for calcium-handling of human embryonic stem cell-derived cardiomyocytes: Insights for driven maturation
Cardiomyocytes (CMs) are nonregenerative. Self-renewable pluripotent human embryonic stem cells (hESCs) can differentiate into… (More)
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2004
2004
Identification and characterization of human HESL, rat Hesl and rainbow trout hesl genes in silico.
Activation of Notch signaling pathway leads to nuclear translocation of Notch intracellular domain (NIC), and transcriptional… (More)
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1993
1993
Molecular characterization of HES-2, a mammalian helix-loop-helix factor structurally related to Drosophila hairy and Enhancer of split.
Drosophila hairy (h) plays a crucial role in early development as a pair-rule segmentation gene. h and its structurally related… (More)
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