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HEMOCHROMATOSIS, TYPE 1

Known as: HEMOCHROMATOSIS, HFE, HFE1 
National Institutes of Health

Related topics

Related topics

21 relations
Abdominal PainAlopeciaAmenorrheaArthropathy

Broader (2)

HemochromatosisHereditary hemochromatosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis.
Highly Cited
2004
Highly Cited
2004
Influence of HFE gene polymorphism on the progression and treatment of chronic hepatitis C
Summary.  We analysed liver histology findings in a large cohort of patients with chronic hepatitis C and in roughly half of them… 
Highly Cited
2003
Highly Cited
2003
A single viral protein HCMV US2 affects antigen presentation and intracellular iron homeostasis by degradation of classical HLA class I and HFE molecules.
HFE is a nonclassical class I molecule that associates with beta 2-microglobulin (beta 2m) and with the transferrin receptor. HFE… 
Review
2003
Review
2003
HFE, the MHC and hemochromatosis: paradigm for an extended function for MHC class I.
HFE was discovered as the hereditary hemochromatosis (HH) gene. It is located on chromosome 6 (6p21.3), 4Mb telomeric to the HLA… 
Review
2001
Review
2001
Hereditary hemochromatosis since discovery of the HFE gene.
BACKGROUND Hereditary hemochromatosis is an inherited disorder of iron metabolism that is characterized by excessive iron… 
2001
2001
Mutations in the HFE gene and their interaction with exogenous risk factors in hepatocellular carcinoma.
The possible role of iron in facilitating the development of liver cancer is still debated. The aims of this study were to define… 
Highly Cited
2000
Highly Cited
2000
A reverse-hybridization assay for the rapid and simultaneous detection of nine HFE gene mutations.
Hereditary hemochromatosis (HH) is a very common autosomal recessive disorder of iron metabolism and frequently associated with… 
Highly Cited
1999
Highly Cited
1999
Are Haemochromatosis Mutations Related to the Severity of Liver Disease in Hepatitis C Virus Infection?
It has been proposed that iron overload may adversely affect liver disease outcome. The recent identification of 2 mutations in… 
Highly Cited
1999
Highly Cited
1999
Inherited HFE‐unrelated hemochromatosis in italian families
Hemochromatosis (HH) is usually caused by the homozygous state for C282Y mutation in the HFE gene. A minority of iron loaded… 
1999
1999
Polymorphism in intron 4 of HFE does not compromise haemochromatosis mutation results
272 nature genetics • volume 23 • november 1999 In the August issue of Nature Genetics, Jeffrey et al.1 described a primer… 
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