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HE3286

Known as: HE-3286 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Effects of Synthetic Anti-Inflammatory Sterol in CB3V-Induced Myocarditis: A Morphological Study on Heart Muscle Tissue
Cell-mediated immune events play a role in the pathogenesis of myocarditis provoked by Group B coxsackievirus (CVB). Studies… 
2014
2014
Combined inhibition of angiotensin II type 1 receptor and ASK1 significantly attenuates autoimmune optic neuritis
Program Number: 5769 Poster Board Number: B0105 Presentation Time: 8:30 AM–10:15 AM Combined inhibition of angiotensin II type 1… 
2013
2013
A synthetic anti‐inflammatory sterol improves insulin sensitivity in insulin‐resistant obese impaired glucose tolerance subjects
To study the activity of HE3286 (17α‐ethynylandrost‐5‐ene‐3β,7β,17β‐triol), an anti‐inflammatory sterol that is active in models… 
2011
2011
Studies of the pharmacology of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol, a synthetic anti-inflammatory androstene.
17α-Ethynyl-androst-5ene-3β, 7β, 17β-triol (HE3286) is an orally bioavailable analogue of androst-5-ene-3β,7β,17β-triol, a non… 
2010
2010
A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats.
Tissue macrophage inflammatory pathways contribute to obesity-associated insulin resistance. Here, we have examined the efficacy… 
2010
2010
Oral treatment with HE3286 ameliorates disease in rodent models of rheumatoid arthritis.
HE3286 (17alpha-ethynyl-5-androstene-3beta, 7beta, 17beta-triol) is an orally bio-available synthetic derivative of naturally… 
2010
2010
HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression
Background17α-Ethynyl-5-androsten-3β, 7β, 17β-triol (HE3286) is a synthetic derivative of an endogenous steroid androstenetriol… 
2009
2009
HE3286: A Novel Synthetic Steroid as an Oral Treatment for Autoimmune Disease
HE3286 (17α‐ethynyl‐5‐androstene‐3β, 7β, 17β‐triol) is a synthetic derivative of a natural anti‐inflammatory steroid, β‐AET (5… 
2009
2009
An Orally Bioavailable Synthetic Analog of an Active Dehydroepiandrosterone Metabolite Reduces Established Disease in Rodent Models of Rheumatoid Arthritis
Dehydroepiandrosterone (DHEA) treatment provides diverse anti-inflammatory benefits in rodent models of diseases, including… 
2007
2007
A New Orally Bioavailable Synthetic Androstene Inhibits Collagen‐Induced Arthritis in the Mouse
Abstract:  Dehydroepiandrosterone (DHEA) has attracted much interest because of its many antiaging, metabolic and immune… 
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