HDAC6 gene

Known as: JM21, protein phosphatase 1, regulatory subunit 90, KIAA0901 
This gene is involved in chromatin remodeling, repression of gene expression and cellular management of misfolded protein-induced stress.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
010203019962018

Papers overview

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Review
2016
Review
2016
Recent years have witnessed an emergence of a new class of therapeutic agents, termed histone deacetylase 6 (HDAC6) inhibitors… (More)
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2013
2013
Neurons from the brains of Alzheimer's disease (AD) and related tauopathy patients contain neurofibrillary tangles composed of… (More)
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Highly Cited
2012
Highly Cited
2012
Mesenchmal stem cells (MSCs) can be differentiated into either adipocytes or osteoblasts, and a reciprocal relationship exists… (More)
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Highly Cited
2010
Highly Cited
2010
TDP-43 is an RNA/DNA-binding protein implicated in transcriptional repression and mRNA processing. Inclusions of TDP-43 are… (More)
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2010
2010
A family with dominant X-linked chondrodysplasia was previously described. The disease locus was ascribed to a 24 Mb interval in… (More)
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Highly Cited
2007
Highly Cited
2007
A prominent feature of late-onset neurodegenerative diseases is accumulation of misfolded protein in vulnerable neurons. When… (More)
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Highly Cited
2007
Highly Cited
2007
The two major intracellular catabolic pathways, the ubiquitin-proteasome system (UPS) and macroautophagy (autophagy), have each… (More)
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2007
2007
To uncover novel histone deacetylase 6 (HDAC6)-selective inhibitors and to elucidate the structural requirements for their… (More)
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Highly Cited
2003
Highly Cited
2003
Protein acetylation, especially histone acetylation, is the subject of both research and clinical investigation. At least four… (More)
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Highly Cited
2000
Highly Cited
2000
A backcrossed population (BC(4)F(2)) derived from a cross between a japonica rice variety, Nipponbare, as the recurrent parent… (More)
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