Skip to search formSkip to main contentSkip to account menu

HDAC6 gene

Known as: JM21, protein phosphatase 1, regulatory subunit 90, KIAA0901 
This gene is involved in chromatin remodeling, repression of gene expression and cellular management of misfolded protein-induced stress.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Cycle ProgressionDevelopmental processHydrolysisTranscriptional Regulation

Narrower (1)

HDAC6 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Copper-Catalyzed Synthesis, Bio-Evaluation, and in Silico Studies of 2-Aryl-N-alkylbenzimidazoles as Neuroprotective Agents
2-aryl-N-alkylbenzimidazole derivatives synthesized by CuI/PPh3 promoted direct coupling of N-alkylbenzimidazoles with aryl… 
2017
2017
Role of HDAC6 in Transcription Factor EB Mediated Clearance of Misfolded Proteins in Chronic Kidney Disease
The autophagy-lysosomal pathway is a homeostatic mechanism to prevent the accumulation of misfolded proteins. Here, we observed a… 
2016
2016
Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice
Cilia are present in most vertebrate tissues with a wide variety of functions, and abnormalities of cilia are linked to numerous… 
2016
2016
Activated Transcription Factor 3 in Association with Histone Deacetylase 6 Negatively Regulates MicroRNA 199a2 Transcription by Chromatin Remodeling and Reduces Endothelin-1 Expression
ABSTRACT Previous studies showed that high levels of placenta growth factor (PlGF) correlated with increased plasma levels of… 
2014
2014
The histone deacetylase inhibitor vorinostat ( SAHA ) increases the susceptibility of uninfected 1 CD 4 + T cells to HIV by increasing the kinetics and efficiency of post-entry viral events 2 3
A. Haqqani, Jonathan Karn and John C. Tilton* 5 6 7 8 9 10 Center for Proteomics and Bioinformatics, 11 Department of Molecular… 
2013
2013
[New synthesis of highly selective inhibitor of histone deacetylase 6--N-hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3b]indol-5-ylmethyl)benzamide--Tubastatin A].
A four-stage synthesis of highly selective inhibitor of histone deacetylase 6--Tubastatin A was carried out. Convenient and… 
2011
2011
Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions
Review
2008
Review
2008
Ubiquitin Proteasome System Stress Underlies Synergistic Killing of Ovarian Cancer Cells by Bortezomib and a Novel HDAC 6 Inhibitor
Purpose: Elevated metabolic activity of ovarian cancer cells causes increased ubiquitinproteasome-system (UPS) stress, resulting… 
2008
2008
Role of the interaction between Tax-1 and histone deacetylase 6 (HDAC6) in HTLV-1 infected cells
598 Human T cell leukaemia virus type-1 (HTLV-1), the first pathogenic retrovirus discovered in humans 27 years ago is the… 
2008
2008
Tubacin, An Inhibitor of HDAC6, Induces Apoptosis of Acute Lymphoblastic Leukemia Cells in Vitro and in Vivo through a Na+/K+ATPase-Dependent Pathway.
Acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer. Despite effective chemotherapy, 25 to 30% of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)