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HDAC6 gene

Known as: JM21, protein phosphatase 1, regulatory subunit 90, KIAA0901 
This gene is involved in chromatin remodeling, repression of gene expression and cellular management of misfolded protein-induced stress.
National Institutes of Health

Related topics

Related topics

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Cell Cycle ProgressionDevelopmental processHydrolysisTranscriptional Regulation

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HDAC6 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A De Novo RAPGEF2 Variant Identified in a Sporadic Amyotrophic Lateral Sclerosis Patient Impairs Microtubule Stability and Axonal Mitochondria Distribution
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is frequently linked to microtubule abnormalities… 
2018
2018
Transactive response DNA binding protein of 43/histone deacetylase 6 axis alleviates H 2O 2‐induced retinal ganglion cells injury through inhibiting apoptosis and autophagy
Oxidative damage is believed to contribute to the pathogenesis of diabetic retinopathy (DR). The current study aimed to detect… 
2016
2016
HSPB3 protein is expressed in motoneurons and induces their survival after lesion-induced degeneration
2016
2016
Inhibition of histone deacetylase 6 restores innate immune cells in the bone marrow in a lethal septic model
BACKGROUND We have previously demonstrated that Tubastatin A, a selective inhibitor of histone deacetylase 6 (HDAC6), improves… 
2016
2016
Functional interplay between cylindromatosis and histone deacetylase 6 in ciliary homeostasis revealed by phenotypic analysis of double knockout mice
Cilia are present in most vertebrate tissues with a wide variety of functions, and abnormalities of cilia are linked to numerous… 
2015
2015
Cep70 regulates microtubule stability by interacting with HDAC6
2014
2014
Inhibition of HDAC6 Modifies Tau Inclusion Body Formation and Impairs Autophagic Clearance
Proteinaceous inclusions in nerve cells and glia are a defining neuropathological hallmark in a variety of neurodegenerative… 
2014
2014
Regulation of Ku70-Bax Complex in Cells
Ku70, a DNA repair factor in the nucleus, also regulates cell death by binding to the apoptotic protein Bax in the cytoplasm… 
2012
2012
Depression of mitochondrial metabolism by downregulation of cytoplasmic deacetylase, HDAC6
2001
2001
Assignment1 of the human histone deacetylase 6 gene (HDAC6) to X chromosome p11.23 by in situ hybridization
Histone deacetylases (HDACs) play a central role in the modification of chromatin structure and thus in the regulation of… 
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