HDAC3 gene

Known as: Histone Deacetylase 3 Gene, HD3, HISTONE DEACETYLASE 3 
This gene plays a role in chromatin remodeling, repression of gene expression and modulation of both cell growth and apoptosis.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Recently, long noncoding RNAs (lncRNAs) were found to be dysregulated in a variety of tumors. However, it remains unknown how and… (More)
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Highly Cited
2012
Highly Cited
2012
Organization of the genome is critical for maintaining cell-specific gene expression, ensuring proper cell function. It is well… (More)
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Highly Cited
2011
Highly Cited
2011
Disruption of the circadian clock exacerbates metabolic diseases, including obesity and diabetes. We show that histone… (More)
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2011
2011
Many human diseases result from the influence of the nutritional environment on gene expression. The environment interacts with… (More)
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Highly Cited
2008
Highly Cited
2008
Rhythmic changes in histone acetylation at circadian clock genes suggest that temporal modulation of gene expression is regulated… (More)
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Highly Cited
2008
Highly Cited
2008
Histone deacetylases (HDACs) are enzymes that modify key residues in histones to regulate chromatin architecture, and they play a… (More)
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Highly Cited
2005
Highly Cited
2005
Transcriptional regulation plays a fundamental role in controlling circadian oscillation of clock gene expression. The orphan… (More)
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2004
2004
Tamoxifen, a breast cancer therapeutic, is a tissue-selective estrogen receptor modulator (SERM), which acts as an antiestrogen… (More)
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Highly Cited
2003
Highly Cited
2003
Polycomb group (PcG) proteins are required to maintain stable repression of the homeotic genes and others throughout development… (More)
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Highly Cited
2000
Highly Cited
2000
We present evidence that both corepressors SMRT and N-CoR exist in large protein complexes with estimated sizes of 1.5-2 MDa in… (More)
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