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HDAC3 gene

Known as: Histone Deacetylase 3 Gene, HD3, HISTONE DEACETYLASE 3 
This gene plays a role in chromatin remodeling, repression of gene expression and modulation of both cell growth and apoptosis.
National Institutes of Health

Related topics

Related topics

9 relations
HDAC1 geneHDAC1 wt AlleleHDAC2 geneHDAC8 gene

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HDAC3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development
Significance Successful rearrangement of the immunoglobulin locus is critical for B-cell development in the bone marrow and the… 
2016
2016
Histone deacetylases 3 ( HDAC 3 ) is highly expressed in cervical cancer and inhibited by siRNA
Objective: To detect the expression of histone deacetylase 3 (HDAC3) in cervical cancer tissue and investigate the inhibition of… 
2013
2013
HDAC3 interacts with sumoylated C/EBPα to negatively regulate the LXRα expression in rat hepatocytes
2012
2012
Regulated Clearance of Histone Deacetylase 3 Protects Independent Formation of Nuclear Receptor Corepressor Complexes*
Background: Nuclear receptor corepressors form complexes with histone deacetylase 3 (HDAC3). Results: Interplay of HDAC3… 
2011
2011
Role for histone deacetylase 3 in maintenance of genome stability
Comment on: Bhaskara S, et al. Cancer Cell 2010; 18:436-47. 
2010
2010
Inhibition of Histone Deacetylase 3 Produces Mitotic Defects Independent of Alterations in Histone H3 Lysine 9 Acetylation and Methylation
The constitutive heterochromatin of the centromere is marked by high levels of trimethylated histone H3 lysine 9 (H3K9) and… 
2009
2009
Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma
Current systemic therapies have little curative benefit for synovial sarcoma. Histone deacetylase (HDAC) inhibitors and the heat… 
2008
2008
Pro-IL-16 Recruits Histone Deacetylase 3 to the Skp2 Core Promoter through Interaction with Transcription Factor GABP1
Pro-IL-16 is a PDZ domain-containing protein expressed in T cells. Our previous work showed that upon activation of normal T… 
2005
2005
Inhibition of histone deacetylase 3 stimulates apoptosis induced by heat shock under acidic conditions in human maxillary cancer
To elucidate the molecular mechanisms for the enhancement of heat-induced apoptosis on exposure to acidic conditions, human… 
2004
2004
Hairless contains a novel nuclear matrix targeting signal and associates with histone deacetylase 3 in nuclear speckles.
Hair follicle cycling is a highly regulated and dynamic cellular process consisting of phases of growth, regression, and… 
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