Skip to search formSkip to main contentSkip to account menu

HDAC2 gene

Known as: YAF1, HISTONE DEACETYLASE 2, Histone Deacetylase 2 Gene 
This gene is involved in chromatin remodeling, repression of gene expression and control of both cell proliferation and differentiation.
National Institutes of Health

Related topics

Related topics

9 relations
HDAC1 geneHDAC1 wt AlleleHDAC3 geneHDAC3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
MicroRNA-92a-3p regulates the expression of cartilage-specific genes by directly targeting histone deacetylase 2 in chondrogenesis and degradation.
Highly Cited
2013
Highly Cited
2013
Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer
Tumor metastasis is the leading cause of death among breast cancer patients. PELP1 (proline, glutamic acid and leucine rich… 
Highly Cited
2013
Highly Cited
2013
MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer.
Highly Cited
2013
Highly Cited
2013
S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration
Dynamic epigenetic modifications play a key role in mediating the expression of genes required for neuronal development. We… 
2013
2013
Inhibition of histone deacetylase 2 mitigates profibrotic TGF-β1 responses in fibroblasts derived from Peyronie's plaque.
Epigenetic modifications, such as histone acetylation/deacetylation, have been shown to play a role in the pathogenesis of… 
2013
2013
Repression of NR4A1 by a chromatin modifier promotes docetaxel resistance in PC‐3 human prostate cancer cells
Highly Cited
2011
Highly Cited
2011
FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer
Vascular endothelial growth factor (VEGF) has a central role in breast cancer development and progression, but the mechanisms… 
Highly Cited
2009
Highly Cited
2009
Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation
Human immunodeficiency virus type 1 (HIV-1) persists in a latent state within resting CD4+ T cells of infected persons treated… 
Highly Cited
2008
Highly Cited
2008
S-nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
Brain-derived neurotrophic factor (BDNF) and other neurotrophins have a vital role in the development of the rat and mouse… 
2003
2003
HoxA10 Represses Gene Transcription in Undifferentiated Myeloid Cells by Interaction with Histone Deacetylase 2*
The homeodomain proteins, HoxA10 and Pbx1a, interact with negative cis elements to repress gene transcription in undifferentiated… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)