HDAC10 gene

Known as: DKFZP761B039, HDAC10, HISTONE DEACETYLASE 10 
This gene plays a role in the regulation of histone acetylation.
National Institutes of Health

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Histone Deacetylase 10Histone DeacetylationHydrolysisTranscriptional Repression
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Papers overview

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2018
2018
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance
Drug resistance is a leading cause for treatment failure in many cancers, including neuroblastoma, the most common solid… (More)
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2017
2017
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Cationic polyamines such as spermidine and spermine are critical in all forms of life, as they regulate the function of… (More)
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2017
2017
HDAC10 as a potential therapeutic target in ovarian cancer.
OBJECTIVE We analyzed histone deacetylase 10 (HDAC10) for function in the context of the DNA damage response in BRCA1-null… (More)
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2016
2016
Isoform-Selective HDAC Inhibitor Therapy for Transplantation: Are We Ready for HDAC6?
The 18 known mammalian histone/protein deacetylases (HDACs) are divided into 4 groups, termed class I (HDAC1,HDAC2,HDAC3… (More)
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2014
2014
Histone deacetylase inhibitors in cancer: what have we learned?
The understanding that epigenetic modification of tumor suppressor genes by histone deacetylases (HDACs) plays a role in… (More)
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2014
2014
Decreased expression of histone deacetylase 10 predicts poor prognosis of gastric cancer patients.
Aberrant expression of histone deacetylase (HDACs) was associated with carcinogenesis and progression of various tumors. However… (More)
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2011
2011
Histone deacetylase in chronic lymphocytic leukemia.
BACKGROUND Elevated histone deacetylase (HDAC) isoenzyme levels have been described in patients with carcinomas and leukemias… (More)
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2008
2008
Proteomic identification of malignant transformation-related proteins in esophageal squamous cell carcinoma.
Esophageal cancer (EC) persists to be a leading cancer-related death in northern China. Clinical outcome of EC is the most dismal… (More)
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2008
2008
The role of histone deacetylase 10 in gamma-globin gene regulation
 
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Highly Cited
2004
Highly Cited
2004
Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients.
HDAC genes are thought to be involved in gene expression through the regulation of chromatin structure, alterations of which may… (More)
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