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HDAC10 gene
Known as:
DKFZP761B039
, HDAC10
, HISTONE DEACETYLASE 10
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This gene plays a role in the regulation of histone acetylation.
National Institutes of Health
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Related topics
Related topics
5 relations
Histone Deacetylase 10
Histone Deacetylation
Hydrolysis
Transcriptional Repression
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Homology modeling of human histone deacetylase 10 and design of potential selective inhibitors
Abdullahi Ibrahim Uba
,
K. Yelekçi
Journal of Biomolecular Structure and Dynamics
2019
Corpus ID: 52182277
Abstract Histone deacetylases (HDACs) are implicated in the pathology of various cancers, and their pharmacological blockade has…
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2019
2019
Binding of N8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation.
C. J. Herbst‐Gervasoni
,
D. Christianson
Biochemistry
2019
Corpus ID: 208184642
Eukaryotic histone deacetylase 10 (HDAC10) is a Zn2+-dependent hydrolase that exhibits catalytic specificity for the hydrolysis…
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Review
2019
Review
2019
Histone deacetylases in stroke
Mei-Han Kao
,
Teng-Nan Lin
Chinese journal of physiology
2019
Corpus ID: 195761660
Stroke is the second leading cause of death and the leading cause of adult disability worldwide. Despite an impressive amount of…
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2019
2019
Characterization of the Role of Host Cellular Factor Histone Deacetylase 10 during HIV-1 Replication
Xiaozhuo Ran
,
Zhujun Ao
,
T. Olukitibi
,
Xiaojian Yao
Viruses
2019
Corpus ID: 209518453
To date, a series of histone deacetylases have been documented to restrict HIV-1 replication at different steps. In this study…
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2018
2018
Rice histone deacetylase 10 and Arabidopsis histone deacetylase 14 genes encode N‐acetylserotonin deacetylase, which catalyzes conversion of N‐acetylserotonin into serotonin, a reverse reaction for…
Kyungjin Lee
,
H. Lee
,
K. Back
Journal of Pineal Research
2018
Corpus ID: 275998
In plants, melatonin production is strictly regulated, unlike the production of its precursor, serotonin, which is highly…
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Highly Cited
2017
Highly Cited
2017
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Y. Hai
,
Stephen A. Shinsky
,
N. J. Porter
,
D. Christianson
Nature Communications
2017
Corpus ID: 13587768
Cationic polyamines such as spermidine and spermine are critical in all forms of life, as they regulate the function of…
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2015
2015
Histone deacetylase inhibitors in cancer: What have we learned?
James R. Whittle
,
J. Desai
Cancer
2015
Corpus ID: 7297985
The understanding that epigenetic modification of tumor suppressor genes by histone deacetylases (HDACs) plays a role in…
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Highly Cited
2012
Highly Cited
2012
Histone Deacetylase in Chronic Lymphocytic Leukemia
J.C. Wang
,
M. Kafeel
,
+7 authors
S. Lichter
Oncology
2012
Corpus ID: 207738153
Background: Elevated histone deacetylase (HDAC) isoenzyme levels have been described in patients with carcinomas and leukemias…
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Highly Cited
2008
Highly Cited
2008
Proteomic identification of malignant transformation‐related proteins in esophageal squamous cell carcinoma
Yi-Jun Qi
,
Qing‐Yu He
,
+6 authors
J. Chiu
Journal of Cellular Biochemistry
2008
Corpus ID: 20492618
Esophageal cancer (EC) persists to be a leading cancer‐related death in northern China. Clinical outcome of EC is the most dismal…
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Highly Cited
2004
Highly Cited
2004
Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients
H. Osada
,
Y. Tatematsu
,
H. Saito
,
Y. Yatabe
,
T. Mitsudomi
,
Takashi Takahashi
International Journal of Cancer
2004
Corpus ID: 23452893
HDAC genes are thought to be involved in gene expression through the regulation of chromatin structure, alterations of which may…
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