HDAC10 gene

Eukaryotic histone deacetylase 10 (HDAC10) is a Zn2+-dependent hydrolase that exhibits catalytic specificity for the hydrolysis… Expand

To date, a series of histone deacetylases have been documented to restrict HIV-1 replication at different steps. In this study… Expand

Stroke is the second leading cause of death and the leading cause of adult disability worldwide. Despite an impressive amount of… Expand

Abstract Histone deacetylases (HDACs) are implicated in the pathology of various cancers, and their pharmacological blockade has… Expand

In plants, melatonin production is strictly regulated, unlike the production of its precursor, serotonin, which is highly… Expand

Cationic polyamines such as spermidine and spermine are critical in all forms of life, as they regulate the function of… Expand

The understanding that epigenetic modification of tumor suppressor genes by histone deacetylases (HDACs) plays a role in… Expand

Background: Elevated histone deacetylase (HDAC) isoenzyme levels have been described in patients with carcinomas and leukemias… Expand

Esophageal cancer (EC) persists to be a leading cancer‐related death in northern China. Clinical outcome of EC is the most dismal… Expand

HDAC genes are thought to be involved in gene expression through the regulation of chromatin structure, alterations of which may… Expand