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HDAC10 gene

Known as: DKFZP761B039, HDAC10, HISTONE DEACETYLASE 10 
This gene plays a role in the regulation of histone acetylation.
National Institutes of Health

Related topics

Related topics

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Histone Deacetylase 10Histone DeacetylationHydrolysisTranscriptional Repression
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Binding of N8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation.
Eukaryotic histone deacetylase 10 (HDAC10) is a Zn2+-dependent hydrolase that exhibits catalytic specificity for the hydrolysis… 
Review
2019
Review
2019
Histone deacetylases in stroke
Stroke is the second leading cause of death and the leading cause of adult disability worldwide. Despite an impressive amount of… 
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2019
2019
Characterization of the Role of Host Cellular Factor Histone Deacetylase 10 during HIV-1 Replication
To date, a series of histone deacetylases have been documented to restrict HIV-1 replication at different steps. In this study… 
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2018
2018
Homology modeling of human histone deacetylase 10 and design of potential selective inhibitors
Abstract Histone deacetylases (HDACs) are implicated in the pathology of various cancers, and their pharmacological blockade has… 
2018
2018
Rice histone deacetylase 10 and Arabidopsis histone deacetylase 14 genes encode N‐acetylserotonin deacetylase, which catalyzes conversion of N‐acetylserotonin into serotonin, a reverse reaction for…
In plants, melatonin production is strictly regulated, unlike the production of its precursor, serotonin, which is highly… 
Highly Cited
2017
Highly Cited
2017
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Cationic polyamines such as spermidine and spermine are critical in all forms of life, as they regulate the function of… 
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2015
2015
Histone deacetylase inhibitors in cancer: What have we learned?
The understanding that epigenetic modification of tumor suppressor genes by histone deacetylases (HDACs) plays a role in… 
Highly Cited
2011
Highly Cited
2011
Histone Deacetylase in Chronic Lymphocytic Leukemia
Background: Elevated histone deacetylase (HDAC) isoenzyme levels have been described in patients with carcinomas and leukemias… 
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Highly Cited
2008
Highly Cited
2008
Proteomic identification of malignant transformation‐related proteins in esophageal squamous cell carcinoma
Esophageal cancer (EC) persists to be a leading cancer‐related death in northern China. Clinical outcome of EC is the most dismal… 
Highly Cited
2004
Highly Cited
2004
Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients
HDAC genes are thought to be involved in gene expression through the regulation of chromatin structure, alterations of which may… 
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