HCK protein, human

Known as: hemopoietic cell kinase protein, human, p61Hck, Hematopoietic Cell Kinase 
Tyrosine-protein kinase Hck (526 aa, ~60 kDa) is encoded by the human HCK gene. This protein plays a role in tyrosine phosphorylation, signaling and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
02419892017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
We have shown previously that tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) is important for diverse… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
Hck is a phagocyte specific proto-oncogene of the Src family expressed as two isoforms, p59Hck and p61Hck. It plays a critical… (More)
Is this relevant?
2004
2004
Interleukin-6 (LI-6) is a known growth and survival factor in multiple myeloma via activation of extracellular signal-regulated… (More)
Is this relevant?
2002
2002
Hck is a protein kinase of the Src family specifically expressed in phagocytes as two isoforms, p59Hck and p61Hck, localized at… (More)
Is this relevant?
2000
2000
Hck, a protein-tyrosine kinase of phagocytes, is the unique member of the Src family expressed under two alternatively translated… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Chronic myeloid leukemia is characterized by the Philadelphia (Ph1) translocation t(9;22) that generates a hybrid gene, bcr/abl… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The human proto-oncogene HCK encodes two versions of a protein-tyrosine kinase, with molecular weights of 59,000 (p59hck) and 61… (More)
Is this relevant?
1995
1995
The src-family protein-tyrosine kinase p59hck is mainly expressed in neutrophils; however, its functional role in these cells is… (More)
Is this relevant?
1995
1995
U937 cells differentiated with IFN-gamma (termed U937IF cells) were used to study Fc gamma RI signaling. IFN induces a functional… (More)
Is this relevant?
1995
1995
Phagocytosis of pathogens and inert particles such as zymosan by macrophages, and related secretory functions require the… (More)
Is this relevant?