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HCK protein, human

Known as: hemopoietic cell kinase protein, human, p61Hck, Hematopoietic Cell Kinase 
Tyrosine-protein kinase Hck (526 aa, ~60 kDa) is encoded by the human HCK gene. This protein plays a role in tyrosine phosphorylation, signaling and… Expand
National Institutes of Health

Papers overview

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2004
2004
Interleukin-6 (LI-6) is a known growth and survival factor in multiple myeloma via activation of extracellular signal-regulated… Expand
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Highly Cited
2003
Highly Cited
2003
ACK1 (activated Cdc42-associated kinase 1) is a nonreceptor tyrosine kinase and the only tyrosine kinase known to interact with… Expand
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Highly Cited
2002
Highly Cited
2002
The adamalysins (ADAMs) are transmembrane glycoproteins involved in cell adhesion and proteolytic ectodomain processing of… Expand
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2002
2002
Hck is a protein kinase of the Src family specifically expressed in phagocytes as two isoforms, p59Hck and p61Hck, localized at… Expand
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Highly Cited
1997
Highly Cited
1997
The protein Hck is a member of the Src family of non-receptor tyrosine kinases which is preferentially expressed in… Expand
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Highly Cited
1997
Highly Cited
1997
Src-family kinases play a central role in regulation of hematopoietic cell functions. We found that mouse erythrocytes express… Expand
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Highly Cited
1995
Highly Cited
1995
The human proto-oncogene HCK encodes two versions of a protein-tyrosine kinase, with molecular weights of 59,000 (p59hck) and 61… Expand
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Highly Cited
1995
Highly Cited
1995
The src-family protein-tyrosine kinase p59hck is mainly expressed in neutrophils; however, its functional role in these cells is… Expand
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1995
1995
The Ras GTPase-activating protein (GAP) is a target for protein tyrosine kinases of both the receptor and cytoplasmic classes and… Expand
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Highly Cited
1987
Highly Cited
1987
We have isolated cDNAs representing a previously unrecognized human gene that apparently encodes a protein-tyrosine kinase. We… Expand
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