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HAAO gene

Known as: 3-hydroxyanthranilate 3,4-dioxygenase, 3-HYDROXYANTHRANILIC ACID DIOXYGENASE, 3-HAO 
National Institutes of Health

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3-Hydroxyanthranilate 3,4-dioxygenase

Papers overview

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2017
2017
Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.
3-Hydroxyanthranilate 3,4-dioxygenase (3HAO) is an enzyme in the microglial branch of the kynurenine pathway of tryptophan… 
2015
2015
Human 3-hydroxyanthranilate 3,4-dioxygenase () dynamics and reaction, a multilevel computational study.
3-Hydroxyanthranilate 3,4-dioxygenase () is a non-heme iron dependent enzyme. It catalyses the cleavage of the benzene ring of 3… 
2013
2013
Enzymes That Control the Conversion of L-Tryptophan-nicotinamide and the Urinary Excretion Ratio (N 1-Methyl-2-pyridone-5-carboxamide + N 1-Methyl-4-pyridone-3-carboxamide)/N 1-Methylnicotinamide in…
There is little information on L-tryptophan→nicotinamide metabolism in mice. In the present study, we investigated the two… 
2013
2013
A DNA methylation assay for detection of ovarian cancer cells using a HpaII/MspI digestion-based PCR assay in an integrated microfluidic system
Early and accurate diagnosis of cancer plays a very important role in favorable clinical outcomes. DNA methylation of tumor… 
2001
2001
QSAR study on inhibition of brain 3-hydroxy-anthranilic acid dioxygenase (3-HAO): a molecular connectivity approach.
2000
2000
Anticonvulsant effects of the 3-hydroxyanthranilic acid dioxygenase inhibitor NCR-631
Summary. The kynurenine pathway intermediate 3-hydroxyanthranilic acid (3-HANA) is converted by 3-HANA 3,4-dioxygenase (3-HAO) to… 
1999
1999
Effects of Mitochondria and O‐Methoxybenzoylalanine on 3‐Hydroxyanthranilic Acid Dioxygenase Activity and Quinolinic Acid Synthesis
Abstract : The use of o‐methoxybenzoylalanine, a selective kynureninase inhibitor, has been proposed with the aim of reducing… 
Review
1999
Review
1999
Regulation of quinolinic acid synthesis by mitochondria and o-methoxybenzoylalanine.
o-Methoxybenzoylalanine, a selective kynureninase inhibitor, caused unexpected accumulation of 3-hydroxyanthranilic acid (3OH-ANA… 
1993
1993
High levels of quinolinic acid in brain of epilepsy-prone E1 mice
1992
1992
Abnormally high activity of 3-hydroxyanthranilate 3,4-dioxygenase in brain of epilepsy-prone El mice
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