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H 1152P

Known as: H-1152P, H1152P 
National Institutes of Health

Papers overview

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2019
2019
Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues.
Highly Cited
2012
Highly Cited
2012
Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL
Highly Cited
2009
Highly Cited
2009
Efficacy of Rho-kinase inhibition in promoting cell survival and reducing reactive gliosis in the rodent retina.
PURPOSE To analyze the outcomes of Rho-kinase (ROCK) inhibition on retinal cell survival and glial reactivity under adverse… 
2009
2009
The Effect of the H-1152P, a Potent Rho-Associated Coiled Coil-Formed Protein Kinase Inhibitor, in Rabbit Normal and Ocular Hypertensive Eyes
Purpose: We wanted to determine the intraocular pressure (IOP)-lowering effect of H-1152P by utilizing a rabbit ocular… 
2008
2008
Detection of myosin light chain phosphorylation--a cell-based assay for screening Rho-kinase inhibitors.
2008
2008
ROCK and PRK‐2 mediate the inhibitory effect of Y‐27632 on polyglutamine aggregation
2007
2007
Surface-plasmon-resonance-based biosensor with immobilized bisubstrate analog inhibitor for the determination of affinities of ATP- and protein-competitive ligands of cAMP-dependent protein kinase.
2007
2007
The Rho-kinase inhibitor H-1152P suppresses the wound-healing activities of human Tenon's capsule fibroblasts in vitro.
PURPOSE To analyze the role of Rho-kinase signaling in the wound-healing activities of human Tenon's capsule fibroblasts by using… 
Highly Cited
2006
Highly Cited
2006
The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity*
ROCK or Rho-associated kinase, a serine/threonine kinase, is an effector of Rho-dependent signaling and is involved in actin… 
Highly Cited
2003
Highly Cited
2003
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
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