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Guanylthiourea

Known as: Gutimine, Guanylthiourea [Chemical/Ingredient], Guthimine 
May protect against hypoxic damage; proposed for treatment of shock due to trauma or blood loss; also stimulates paretic gastrointestinal system.
National Institutes of Health

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7 relations
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Design, synthesis and biological evaluation of 4-aminoquinoline-guanylthiourea derivatives as antimalarial agents.
Review
2019
Review
2019
Enhancement of physical endurance in animals by means of compounds with thiourea group (review of literature)
At the Department of Pharmacology of the S.M. Kirov Military Medical Academy, Saint Petersburg, Russia, a number of chemical… 
2017
2017
Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in vivo and molecular modelling studies.
2008
2008
Thiourea and Thiosemicarbazide Derivatives Structure, Reactions, and Pharmacological Activity. 10. Synthesis and Pharmacological and Pharmacokinetic Properties of the New Antihypoxic and…
Pharmacological studies of the new triazinoindole tompasline (3-(2-morpholinoethylthio)-1,2,4-triazino[5, 6-b]indole… 
2004
2004
Effect of some antihypoxic agents on cyclic nucleotide concentrations in brain structures under normal and hypoxic conditions
We know that cyclic nucleotides take part in the regulation of every biologically important process [i]. Accordingly, in the… 
1997
1997
Thiourea and thiosemicarbazide derivatives: Structure, transformations, and pharmacological activity. Part II. Antihypoxic activity of 1,2,4-triazino[5,6-b]indole derivatives
1993
1993
[The use of sodium gamma-oxybutyrate and gutimine for decreasing metabolic disorders in the heart, caused by exotoxic shock in acetic acid poisoning].
Exotoxic shock was simulated in non-linear rat males anesthetized with barbital after intragastric administration of 70% acetic… 
1986
1986
Effects of nitrification inhibitors on denitrification of nitrate in soil
SummaryThe influence of 28 nitrification inhibitors on denitrification of nitrate in soil was studied by determining the effects… 
1984
1984
Effect of gutimine on the electroencephalogram and cerebral blood supply of cats with intracerebral hemorrhage
It was shown in experiments on conscious cats 1-2 days after intracerebral hemorrhage (administration of 2 ml autogenous blood in… 
1962
1962
The radioprotective action of guanylthiourea and related compounds.
SummaryCompounds incorporating the thioureido and guanidino structures have been tested for protective action against 900 r whole… 
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