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Guanylthiourea

Known as: Gutimine, Guanylthiourea [Chemical/Ingredient], Guthimine 
May protect against hypoxic damage; proposed for treatment of shock due to trauma or blood loss; also stimulates paretic gastrointestinal system.
National Institutes of Health

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7 relations
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Effect of some antihypoxic agents on cyclic nucleotide concentrations in brain structures under normal and hypoxic conditions
We know that cyclic nucleotides take part in the regulation of every biologically important process [i]. Accordingly, in the… 
1997
1997
Thiourea and thiosemicarbazide derivatives: Structure, transformations, and pharmacological activity. Part II. Antihypoxic activity of 1,2,4-triazino[5,6-b]indole derivatives
1993
1993
[The use of sodium gamma-oxybutyrate and gutimine for decreasing metabolic disorders in the heart, caused by exotoxic shock in acetic acid poisoning].
Exotoxic shock was simulated in non-linear rat males anesthetized with barbital after intragastric administration of 70% acetic… 
1993
1993
[Effect of using gutimine in the pre-ischemic period on myocardial phospholipids during reperfusion].
Physico-chemical properties of phospholipids were studied in heart muscle at postischemic period after preventive treatment with… 
1987
1987
[Dissociation of the anti-amnesic and antihypoxic effects of nootropic and antihypoxic preparations].
In experimental studies on mice it was shown that piracetam, Cleregil, centrophenoxine, pyritinol possessed the most pronounced… 
1986
1986
Corrective effect of gutimine on the body in hypoxia
1983
1983
[Application of the methods of the mathematical theory of experiments to the development of multicomponent radioprotective preparations].
A study was made of the possibility of using a mathematical theory of experiment in developing effective many-component… 
1975
1975
[Effect of phenamine and gutimine and gutimine on adaptive changes in arterial pressure occurring during skeletal muscle contraction].
Effects of amphetamine (0,1--11 mg/kg) and gutimin (5--50 mg/kg) on the pressor reflex originating in the exercising muscle were… 
1975
1975
Effect of phenamine and gutimine and gutimine on adaptive changes in arterial pressure occurring during skeletal muscle contraction
Effects of amphetamine (0,1--11 mg/kg) and gutimin (5--50 mg/kg) on the pressor reflex originating in the exercising muscle were… 
1962
1962
The radioprotective action of guanylthiourea and related compounds.
SummaryCompounds incorporating the thioureido and guanidino structures have been tested for protective action against 900 r whole… 
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