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A Global Agenda for Advancing Freshwater Biodiversity Research
Freshwater biodiversity is declining dramatically, and the current biodiversity crisis requires defining bold goals and mobilizing substantial resources to meet the challenges. While the reasons are… Expand
[The matrix metalloproteinase 9 (MMP-9) and TIMP-1 activities in patients with chronic and recurrent pancreatitis].
In aggravation mechanisms of chronic recurrent pancreatitis take part the increase synthesis of MMP-9 after TNOalpha and IL-1beta activation, and addition to therapy of pancreatitis the Mexidol helps to decrease M MP-9 level and to increase the synthesis of TIMP-1. Expand
[The participation of matrix metalloproteinases-9 and TIMP-1 in formation of atrial fibrillation paroxisms in patients with metabolic syndrome].
In patients with metabolic syndrome in combination with paroxysmal form of atrial fibrillation the significant increase synthesis of MMP-9 level can lead to increase of atriansms because of increased synthesis of collagen tissue in myocard and vessel walls. Expand
Prevention of heart damage of sodium oxybutyrate in terminal states caused by acute blood loss
After clinical death caused by acute blood loss, hearts of rats were essentially damaged, but these effects could be prevented by gamma-hydroxybutyric acid, an endogenous metabolite having central inhibitory effect, which was administered to the animals before the loss of blood. Expand
Efficacy of ivabradine in combination therapy for complicated acute coronary syndrome in patients with type 2 diabetes mellitus
Ivabradine therapy demonstrated antiischemic and antianginal efficiencies and a good tolerability, without leading to the development of tolerance and without being followed by the developmentof the withdrawal syndrome. Expand
Prevention of impairment of myocardium metabolism and function in immobilization stress using previous adaptation to short stress exposures
A long-term immobilization stress was shown to cause a distinct enzymemia in rats, and a distinctly increased penetration of aspartate transferase, lactate- and malate dehydrogenases and RNAase into coronary circulation was found in isolated heart of the animals. Expand
[The effect of preliminary administration of the beta-blocker inderal on the course of the postresuscitation period].
- Dolgikh Vt
- 1 September 1989
It has been shown that inderal, retaining phospholipid content of cardiomyocyte membranes, reduces the electrical heart instability and completely prevents ventricular fibrillation in the early postresuscitation period. Expand
[Prevention with inderal of post-resuscitation impairment of metabolism in heart and brain tissues].
- Dolgikh Vt
: Restriction of lipolysis as well as a decrease in the rate of lipid peroxidation due to prevention of inhibition of antioxidant enzymes and to maintaining of bioantioxidants in heart and brain… Expand
[The use of sodium gamma-oxybutyrate and gutimine for decreasing metabolic disorders in the heart, caused by exotoxic shock in acetic acid poisoning].
Exotoxic shock was simulated in non-linear rat males anesthetized with barbital after intragastric administration of 70% acetic acid at a dose of 4 ml/kg using a gastric tube. Energy metabolism and… Expand
[Prevention of post-resuscitation impairment of energy metabolism in the myocardium using sodium gamma-hydroxybutyrate, ionol and gutimine].
- Dolgikh Vt
Impairments of energy metabolisms in myocardium were found in rats after clinical death caused by acute hemorrhage and preadministration of gamma-aminobutyric acid, ionol and gutimine decreased these impairments as well as the postresuscitation lethality. Expand