Guanfacine

Known as: Guanfacina, Guanfacinum, Guanfacine [Chemical/Ingredient] 
A centrally acting adrenergic agonist with non-stimulant and antihypertensive property. Guanfacine selectively stimulates alpha-2 adrenergic… (More)
National Institutes of Health

Papers overview

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2012
2012
Cocaine dependence is associated with increased stress and drug cue-induced craving and physiological arousal but decreased… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE This study compared the efficacy of guanfacine extended release (GXR), a selective alpha(2A)-adrenoceptor agonist, with… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE With this study we assessed the efficacy and safety of an extended-release formulation of guanfacine compared with… (More)
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2006
2006
OBJECTIVE The authors report an 8-week, double-blind, randomized controlled trial of guanfacine versus placebo for posttraumatic… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE This study evaluated the efficacy and safety of guanfacine in treating children with tic disorders and attention… (More)
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2001
2001
Norepinephrine plays a significant role in the working memory functions of the prefrontal cortex by its actions at alpha-2a… (More)
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Highly Cited
1999
Highly Cited
1999
The present study compares, using a double-blind, placebo controlled design the effects of two α2-agonists, clonidine (0.5, 2… (More)
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Highly Cited
1995
Highly Cited
1995
OBJECTIVE Medications such as clonidine have been shown to facilitate calming, to enhance frustration tolerance, and to reduce… (More)
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Highly Cited
1995
Highly Cited
1995
OBJECTIVE Many children with Tourette's syndrome (TS) are handicapped more by difficulties with inattention, impulsivity, and… (More)
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Highly Cited
1988
Highly Cited
1988
The present study attempted to identify an alpha-2 agonist that could improve working memory in aged nonhuman primates without… (More)
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