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Growth Differentiation Factor 2

Known as: BMP-9, Bone Morphogenetic Protein 9, Growth Differentiation Factor 2 [Chemical/Ingredient] 
A growth differentiation factor that plays a regulatory role as a paracrine factor for a diverse array of cell types during EMBRYONIC DEVELOPMENT and… Expand
National Institutes of Health

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Related topics

11 relations
GDF2 geneGDF2 wt AlleleIn BloodProcess of secretion
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Growth/Differentiation Factor 2, human

Papers overview

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Highly Cited
2012
Highly Cited
2012
Structural and Functional Insights into Endoglin Ligand Recognition and Binding
Endoglin, a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells, is a… Expand
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Highly Cited
2012
Highly Cited
2012
Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium.
The importance of morphogenetic proteins (BMPs) and their antagonists in vascular development is increasingly being recognized… Expand
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Highly Cited
2011
Highly Cited
2011
BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential.
Promoting osteogenic differentiation and efficacious bone regeneration have the potential to revolutionize the treatment of… Expand
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Highly Cited
2010
Highly Cited
2010
BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo
Members of the bone morphogenetic protein (BMP) family have been implicated in the development and maintenance of vascular… Expand
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Highly Cited
2008
Highly Cited
2008
Bone Morphogenetic Protein-9 Induces Apoptosis in Prostate Cancer Cells, the Role of Prostate Apoptosis Response-4
Bone morphogenetic proteins (BMP) have been implicated in the development of bone metastases in prostate cancer. In this study… Expand
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Highly Cited
2004
Highly Cited
2004
Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery
Efficacious bone regeneration could revolutionize the clinical management of bone and musculoskeletal disorders. Although several… Expand
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Highly Cited
2002
Highly Cited
2002
Ex Vivo Bone Morphogenetic Protein-9 Gene Therapy Using Human Mesenchymal Stem Cells Induces Spinal Fusion in Rodents
OBJECTIVE Ex vivo gene therapy with the use of human mesenchymal stem cells (hMSCs) and bone morphogenetic protein (BMP) genes… Expand
Highly Cited
2000
Highly Cited
2000
Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9.
Bone morphogenetic proteins (BMPs) have multiple functions in the developing nervous system. A member of this family, BMP-9, was… Expand
Highly Cited
2000
Highly Cited
2000
Bone Morphogenetic Protein-9
Bone morphogenetic proteins (BMPs) occupy important roles during development serving to direct cells through specific… Expand
Highly Cited
1995
Highly Cited
1995
Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation.
A new member of the transforming growth factor (TGF)-beta superfamily, BMP-9, has recently been identified and shown to be… Expand
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