Growth Differentiation Factor 2

Known as: BMP-9, Bone Morphogenetic Protein 9, Growth Differentiation Factor 2 [Chemical/Ingredient] 
A growth differentiation factor that plays a regulatory role as a paracrine factor for a diverse array of cell types during EMBRYONIC DEVELOPMENT and… (More)
National Institutes of Health

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GDF2 geneGDF2 wt AlleleIn BloodProcess of secretion
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Growth/Differentiation Factor 2, human

Papers overview

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2013
2013
Low-level laser therapy enhances the expression of osteogenic factors during bone repair in rats
The aim of this study was to evaluate the effects of low-level laser therapy (LLLT) on bone formation, immunoexpression of… (More)
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Highly Cited
2011
Highly Cited
2011
BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential.
Promoting osteogenic differentiation and efficacious bone regeneration have the potential to revolutionize the treatment of… (More)
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2009
2009
Murine preosteoblast differentiation induced by a peptide derived from bone morphogenetic proteins-9.
Bone morphogenetic proteins (BMPs) increase the differentiation of osteoblasts implicated in bone formation and repair. In a… (More)
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2008
2008
Bone morphogenetic protein-9 induces apoptosis in prostate cancer cells, the role of prostate apoptosis response-4.
Bone morphogenetic proteins (BMP) have been implicated in the development of bone metastases in prostate cancer. In this study… (More)
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2007
2007
Differentiation of preosteoblasts using a delivery system with BMPs and bioactive glass microspheres
Bone morphogenetic proteins (BMPs) and 45S5 Bioglass® microspheres (bioactive GM) can increase the differentiation of osteoblasts… (More)
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Highly Cited
2005
Highly Cited
2005
Crystal structure of BMP-9 and functional interactions with pro-region and receptors.
Bone morphogenetic proteins (BMPs), a subset of the transforming growth factor (TGF)-beta superfamily, regulate a diverse array… (More)
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2003
2003
Human mesenchymal stem cells transduced with recombinant bone morphogenetic protein-9 adenovirus promote osteogenesis in rodents.
The present study was undertaken to determine whether ex vivo bone morphogenetic protein-9 (BMP-9) gene therapy using human… (More)
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2002
2002
Ex vivo bone morphogenetic protein-9 gene therapy using human mesenchymal stem cells induces spinal fusion in rodents.
OBJECTIVE Ex vivo gene therapy with the use of human mesenchymal stem cells (hMSCs) and bone morphogenetic protein (BMP) genes… (More)
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2001
2001
Morphologic analysis of BMP-9 gene therapy-induced osteogenesis.
The present study was performed to determine the histological, ultrastructural, and radiographic changes that occur over time at… (More)
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Highly Cited
2000
Highly Cited
2000
Induction and maintenance of the neuronal cholinergic phenotype in the central nervous system by BMP-9.
Bone morphogenetic proteins (BMPs) have multiple functions in the developing nervous system. A member of this family, BMP-9, was… (More)
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