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GDF2 wt Allele

Known as: BMP-9, Growth Differentiation Factor 2 wt Allele, BMP9 
Human GDF2 wild-type allele is located in the vicinity of 10q11.22 and is approximately 5 kb in length. This allele, which encodes growth… 
National Institutes of Health

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Angiogenic ProcessCell Differentiation processCell Proliferation Regulatory ProcessDevelopmental process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
[p38 MAPK pathway mediated BMP9-induced osteogenetic differentiation of hPDLSCs].
PURPOSE To determine the effect of p38 MAPK signaling pathway on BMP9-induced osteogenetic differentiation of human periodontal… 
2017
2017
BMP9 induces osteogenesis and adipogenesis in the immortalized human cranial suture progenitors from the patent sutures of craniosynostosis patients
The cranial suture complex is a heterogeneous tissue consisting of osteogenic progenitor cells and mesenchymal stem cells (MSCs… 
2017
2017
Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells
ABSTRACT Hereditary hemorrhagic telangiectasia is characterized by the formation of abnormal vascular networks and caused by the… 
2015
2015
Inactivation of the Phosphatidylinositol 3‐Kinase/Akt Pathway is Involved in BMP9‐mediated Tumor‐suppressive Effects in Gastric Cancer Cells
Bone morphogenetic proteins (BMPs) are members of the TGF‐β superfamily signaling factors. Expression of several BMPs (BMP2, BMP4… 
2015
2015
BMP9 inhibits the proliferation of human lung adenocarcinoma A549 cells through BMPs/SMAD signaling pathway
Objective: To investigate the inhibitory effect of bone morphogenetic protein 9 (BMP9) on the proliferation of human lung… 
2014
2014
BMP9, BMP10, and ALK1: An Emerging Vascular Signaling Pathway with Therapeutic Applications
Bone morphogenetic proteins (BMPs) are growth factors of the TGFs family. Among them, BMP9 and BMP10 have been shown to bind with… 
2014
2014
Phase 1 study of PF-03446962 (anti-ALK-1 mAb) in hepatocellular carcinoma (HCC): Correlation of tumor and serum biomarker data with disease control.
4095 Background: PF-03446962 ,a fully human IgG2 mAb against ALK-1 (Activin-Receptor Like Kinase-1, a specific TGF-β receptor… 
Review
2013
Review
2013
From skeletal to non skeletal: The intriguing roles of BMP-9: A literature review
In the well-known superfamily of transforming growth factors beta (TGF-), bone morphogenetic proteins (BMPs) are one of the most… 
2013
2013
Inhibition of tumor growth in a VEGFR TKI-resistant model of renal cell carcinoma using dalantercept combined with sunitinib.
370 Background: Antagonists of VEGF/VEGFR pathway have demonstrated clinical utility in patients with metastatic renal cell… 
2011
2011
[Hepatic lineage differentiation of hepatic progenitor cells by bone morphogenetic protein or leukemia inhibitory factor].
OBJECTIVE To search for the optimal approach for hepatocyte-directed differentiation of hepatic progenitor cells and investigate… 
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