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GDF2 gene

Known as: GDF2, growth differentiation factor 2, BMP-9 
This gene is involved in the inhibition of angiogenesis.
National Institutes of Health

Related topics

Related topics

12 relations
Angiogenic ProcessCell Differentiation processCell Proliferation Regulatory ProcessDevelopmental process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
BMP9/COX‐2 axial mediates high phosphate‐induced calcification in vascular smooth muscle cells via Wnt/β‐catenin pathway
Vascular calcification is a notable risk factor for cardiovascular system. High phosphate can induce calcification in vascular… 
2017
2017
Growth factor delivery of BMP9 using a novel natural bovine bone graft with integrated atelo-collagen type I: Biosynthesis, characterization, and cell behavior.
Within the past years, BMP9 has been characterized as one of the most osteogenic bone-inducers among the BMP family, however up… 
2017
2017
Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice
Alzheimer’s disease (AD) is the most common type of dementia and has no effective therapies. Previous studies showed that bone… 
2016
2016
Compound genetically engineered mouse models of cancer reveal dual targeting of ALK1 and endoglin as a synergistic opportunity to impinge on angiogenic TGF-β signaling
Angiogenesis occurs early in tumor development, sustains primary tumor growth and provides a route for metastatic escape. The TGF… 
2015
2015
Synergistic effect of BMP9 and TGF-β in the proliferation and differentiation of osteoblasts.
We investigated the synergistic effect of bone morphogenetic protein 9 (BMP9) and transforming growth factor (TGF)-b in the… 
2015
2015
Inactivation of the Phosphatidylinositol 3‐Kinase/Akt Pathway is Involved in BMP9‐mediated Tumor‐suppressive Effects in Gastric Cancer Cells
Bone morphogenetic proteins (BMPs) are members of the TGF‐β superfamily signaling factors. Expression of several BMPs (BMP2, BMP4… 
2013
2013
Fibroblast growth factor 2 inhibits bone morphogenetic protein 9-induced osteogenic differentiation of mesenchymal stem cells by repressing Smads signaling and subsequently reducing Smads dependent…
2012
2012
BMP9-Induced Osteogenetic Differentiation and Bone Formation of Muscle-Derived Stem Cells
Efficient osteogenetic differentiation and bone formation from muscle-derived stem cells (MDSCs) should have potential clinical… 
2011
2011
Bioinformatic Analysis of Pathogenic Missense Mutations of Activin Receptor Like Kinase 1 Ectodomain
Activin A receptor, type II-like kinase 1 (also called ALK1), is a serine-threonine kinase predominantly expressed on endothelial… 
2010
2010
Functional analysis of the BMP 9 response of ALK 1 mutants from HHT 2 patients : a diagnostic tool for novel ACVRL 1 mutations
1Inserm, U878, Grenoble; 2Commissariat à l’Energie Atomique et aux Energies Alternatives, Institut de Recherches en Technologies… 
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