Glycodeoxycholic Acid

Known as: Glycine, N-((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)-, Acid, Glycodeoxycholic, Deoxycholylglycine 
A bile salt formed in the liver by conjugation of deoxycholate with glycine, usually as the sodium salt. It acts as a detergent to solubilize fats… (More)
National Institutes of Health

Papers overview

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2014
2014
Acetaminophen (APAP)-induced acute liver failure (ALF) remains a major clinical problem. Although a majority of patients recovers… (More)
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2013
2013
Bile acids (BAs) have many physiological roles and exhibit both toxic and protective influences within the liver. Alterations in… (More)
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Highly Cited
2012
Highly Cited
2012
Bile acids have been shown to be important regulatory molecules for cells in the liver and gastrointestinal tract. They can… (More)
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2010
2010
The injurious effect of nonsteroidal anti-inflammatory drugs (NSAIDs) in the small intestine was not appreciated until the… (More)
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Highly Cited
2009
Highly Cited
2009
The oral glucose tolerance test (oGTT) is a common tool to provoke a metabolic challenge for scientific purposes, as well as for… (More)
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Highly Cited
1998
Highly Cited
1998
The mechanisms by which inulin may elicit its lipid-lowering effect are not well elucidated. To examine the lipid-lowering… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Reflux of duodenal contents into the esophagus of patients with gastroesophageal reflux disease has been suggested by… (More)
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1995
Highly Cited
1995
Bile salt hydrolase (BSH) activity was shown to be constitutive and substrate-specific: the BSH isogenic Lactobacillus plantarum… (More)
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Highly Cited
1992
Highly Cited
1992
Existing models of acute pancreatitis have limitations to studying novel therapy. Whereas some produce mild self-limited… (More)
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Highly Cited
1991
Highly Cited
1991
To test whether bile acids interact with mast cells, dilute, aqueous solutions of five pure unconjugated natural bile acids and… (More)
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