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Gluthathione synthetase deficiency

Known as: Pyroglutamic Aciduria, 5-Oxoprolinuria, Deficiency of Glutathione Synthetase 
An autosomal recessive genetic disorder caused by mutation(s) in the GSS gene, encoding glutathione synthetase. Mutation(s) in the same gene is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Abstract Vapor Pressure Deficit (VPD) is a principle mediator of global terrestrial CO 2 uptake and water vapor loss through… Expand
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Review
2007
Review
2007
Glutathione is a tripeptide composed of glutamate, cysteine and glycine. Glutathione is present in millimolar concentrations in… Expand
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Review
2005
Review
2005
  • Runa Njålsson
  • Cellular and Molecular Life Sciences CMLS
  • 2005
  • Corpus ID: 59244
Abstract.Glutathione (GSH), one of the most important antioxidants in the eukaryotic organism, is synthesized in a two-step… Expand
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2000
2000
OBJECTIVE To report four cases of pyroglutamic acidemia in adults causing clinically significant acidosis. DATA SOURCES… Expand
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1999
1999
UNLABELLED In patients with defects in the synthesis, breakdown and metabolism of glutathione (GSH), like glutathione synthetase… Expand
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Highly Cited
1999
Highly Cited
1999
Glutathione synthetase (GS) catalyses the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent… Expand
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Highly Cited
1998
Highly Cited
1998
We describe biochemical and clinical features of 11 subjects (ages, 1.2-84 years, nine females and two males) with transient 5… Expand
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Highly Cited
1995
Highly Cited
1995
I. INTRODUCTION II. PERSPECTIVES III. GENERAL THEMES IV. CANCER V. CHROMOSOMES VI. DIAGNOSTIC APPROACHES VII. CARBOHYDRATES VIII… Expand
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1987
1987
1. The evidence is accumulating to suggest that glycine, the simplest amino acid, is conditionally essential in man. Benzoic acid… Expand
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Highly Cited
1975
Highly Cited
1975
Gamma-Glutamyl-cysteine synthetase is inhibited by glutathione under conditions similar to those which prevail in vivo, thus… Expand
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