Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids.
- G. Ahlborg, P. Felig, L. Hagenfeldt, R. Hendler, J. Wahren
- BiologyJournal of Clinical Investigation
- 1 April 1974
Blood glucose levels fall because hepatic glucose output fails to keep up with augmented glucose utilization by the exercising legs, and augmented secretion of glucagon may play an important role in the metabolic adaptation to prolonged exercise by its stimulatory influence on hepatic glycogenolysis and gluconeogenesis.
Utilization of blood‐borne and intramuscular substrates during continuous and intermittent exercise in man.
- B. Essén, L. Hagenfeldt, L. Kaijser
- BiologyJournal of Physiology
- 1 February 1977
The metabolic response to intermittent exercise was found to be similar to that found in continuous exercise with approximately the same average power output and oxygen uptake, which indicates that some factor in the intermediary metabolism functions as a regulator retarding glycolysis and favouring lipid utilization and an aerobic energy release in intermittent exercise.
Influence of glucose and fructose ingestion on the capacity for long-term exercise in well-trained men.
- O. Björkman, K. Sahlin, L. Hagenfeldt, J. Wahren
- MedicineClinical Physiology
- 1 December 1984
Intermittent glucose ingestion during prolonged, heavy bicycle exercise postpones exhaustion and exerts a glycogen-conserving effect in the working muscles, and fructose ingestion during exercise maintains the glucose concentration at the basal level but fails to influence either muscle glycogen degradation or endurance performance.
Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus.
- J. Wahren, P. Felig, L. Hagenfeldt
- BiologyJournal of Clinical Investigation
- 1 April 1976
The inter-organ flux of substrates after a protein-rich meal was studied in seven healthy subjects and in eight patients, with diabetes mellitus, and there was a large amino acid release from the splanchnic bed predominantly involving the branched chain amino acids.
Alterations of mitochondrial function and correlations with personality traits in selected major depressive disorder patients.
- A. Gardner, A. Johansson, T. Hällström
- Medicine, PsychologyJournal of Affective Disorders
- 1 September 2003
Splanchnic and leg exchange of glucose, amino acids, and free fatty acids during exercise in diabetes mellitus.
- J. Wahren, L. Hagenfeldt, P. Felig
- MedicineJournal of Clinical Investigation
- 1 June 1975
Exercise in diabetic patients with mild ketosis is associated with a rise in blood glucose and FFA levels as well as augmented splanchnic production and peripheral uptake of ketone bodies and is concluded that glucose uptake by exercising muscle in hyperglycemic diabetics is no different from that of controls.
Influence of lactate infusion on glucose and FFA metabolism in man.
- G. Ahlborg, L. Hagenfeldt, J. Wahren
- Medicine, BiologyScandinavian Journal of Clinical and Laboratory…
- 1 March 1976
The fractional uptake of lactate by the leg, the splanchnic region, and the forearm decreased during the course of the infusion, and sodium L(+)-lactate levels were 3 to 5 mmol/l during the infusion.
3-Hydroxydicarboxylic aciduria--a fatty acid oxidation defect with severe prognosis.
- L. Hagenfeldt, U. von Döbeln, L. Lindeberg
- MedicineJornal de Pediatria
- 1 March 1990
Benefits of Neonatal Screening for Congenital Adrenal Hyperplasia (21-Hydroxylase Deficiency) in Sweden
- A. Thilén, A. Nordenström, L. Hagenfeldt, U. von Döbeln, C. Guthenberg, A. Larsson
- MedicinePediatrics
- 1 April 1998
The main benefits of screening were avoidance of serious salt loss crises, earlier correct gender assignment in virilized girls, and detection of patients who would have otherwise been missed in the neonatal period.
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